Calculate the pI of Histidine (pKa’s = 2.3, 6.04, 9.33)
6.11
7.68
3.08
2.35
4.07

Answers

Answer 1

Answer:

The correct answer is 7.68

Explanation:

Isoelectric point (pI) is the pH at which the amino acid has net a charge of zero. We have to choose the two values of pKa at which the neutral form of the amino acid is predominant. Histidine (Hys) is a basic amino acid. From pKa's data, we deduce:

pKa1 = 2.3 (corresponds to α- carboxyl group)

pKa2= 6.04 (corresponds to R group)

pKa3= 9.33 (corresponds to α- amino group)

Since it is a basic amino acid, the neutral form will exist between the higher pKa's values. Thus, the pI will be in a pH value between 6.3 and 9.33.

So, we have to calculate the average of pKa2 and pKa3:

pI= (pKa2+pKa3)/2= (6.04+9.33)/2= 7.68

Therefore, the pI of Hys is 7.68.


Related Questions

Which nerve is responsible for weakness in climbing stairs or jumping?
A. Tibial
B. Superior gluteal
C. Inferior gluteal
D. Obturator
E. Femoral

Answers

Answer:

C. Inferior gluteal

Explanation:

The inferior gluteal nerve has a rich concentration in the gluteus maximus muscle. This muscle is located in the hip region. These nerves are primarily responsible for the ability of the gluteus maximus to move and performs some functions during motion.

An example of such function involves the extension of the hip to the thigh in movements such as climbing stairs, hiking, squatting etc.

How does exponential growth differ from logistic growth? R‐selected species have exponential growth rates, whereas K‐selected species always experience logistic growth. Exponential growth occurs when the population is at its biotic potential, whereas logistic growth is limited by the carrying capacity of the environment. Exponential growth is expressed as doubling time, whereas logistic growth is expressed as a percentage change. Exponential growth occurs when a population is very large, whereas logistic growth occurs when a population is at its minimum viable number. Exponential growth results in a J‐shaped curve, whereas logistic growth results in an S‐shaped curve.

Answers

Answer:

Exponential growth occurs when the population is at its biotic potential, whereas logistic growth is limited by the carrying capacity of the environment.

Explanation:  

A population that exhibits a logistic growth model, depends on density, the natality and mortality rate depends on the population size, which means that there is no independence between population growth and population density.

When a population grows in a limited space, density rises gradually and eventually affects the multiplication rate. The population's per capita growth rate decreases as population size increases. The population reaches a maximum point delimited by available resources, such as food or space. This point is known as the carrying capacity, K.

K is a constant that coincides with the size of the population at the equilibrium point when the natality rate and the mortality rate get qual to each other.

If the population size, N, is inferior to K (N<K) the population can still grow. When N approximates to K, the population´s growth speed decreases. When N=K, the population reaches equilibrium, and when N is superior to K (N>K) the population must decrease in size because there are not enough resources to maintain that size.  

The sigmoid curve represents the logistic growth model. At the beginning population grow slowly. In the exposed example this occurred when the small group of 10 foxes moved to the new environment, starting a new population. In the second stage, the population size increases rapidly. Probably this happened when foxes reached a number of 40 individuals. And finally, slow and gradually, the population reaches the equilibrium point, K, which depends on resource availability. This point belongs to the stage where food starts to become harder to find, and much of the living space is occupied.

A population that exhibits an exponential growth model increases in proportion to its size. The increase in the population size depends on the individual´s reproduction rate: a population that grows at constant exponential rate gains individuals faster as the population increases in size.

This model is based on unlimited resource availability which means that there is no effect depending on density. There is no competition for resources. Natality and mortality rate do not depend on density. There is a constant growth rate per capita and it is proportional to the population size.

How does the injection of insulin affect the signal transduction pathway of type 1 diabetics?
a. Injected insulin prevents the glucose from binding to cellular protein receptor.
b. Insulin acts as a secondary messenger that cascades the message to allow glucose into the cell.
c. Insulin is absorbed into the cytoplasm and binds with the transcription factor to make it active.
d. Protein receptors on the cell bond to the insulin, which allows glucose to enter the cell.

Answers

Answer:

The correct answer is D.

Explanation:

To act on target cells, insulin binds to a specialized protein that is located on the membrane of your target cells: the insulin receptor. When insulin binds to the receptor, it activates a cascade of signals within the cell (a process called signal transduction), which is essential for insulin to have an effect on its target tissues. Insulin increases the entry of glucose into cells and causes the number of certain proteins specialized in glucose transport to increase in the membrane of their target cells, such as adipocytes (adipose tissue cells) and skeletal muscle cells.

Answer:

The correct answer is B, b. Insulin acts as a secondary messenger that cascades the message to allow glucose into the cell.

Clio has a vegetable garden and wants to increase the amount of nitrogen in the soil how can she most likely do this.



Please help me​

Answers

She would use a weed enhancer it grows the plants quickly but it doesn't do it naturally it's forceful so I don't recommend

Look at the graphic in the section "What Are the Steps In The Scientific Method?"

According to the article, what is represented by the step called "Hypothesis"?

Answers

Answer:

Brief description of the Orginal experiment state what was done

Explanation:

What did you change?

How did the changes help answer the question

A two-year-old weighing 25.2 lb is admitted to the hospital with fever and diarrhea. Normally the child weighs 29.6 lb. How much fluid (in liters) needs to be replaced in the child's system?a. 1Lb. 1.75 Lc. 2 Ld. 4.4 L

Answers

Answer: C.) 2L

Explanation:

Given the question :

A two-year-old weighing 25.2 lb is admitted to the hospital with fever and diarrhea. Normally the child weighs 29.6 lb. How much fluid (in liters) needs to be replaced in the child's system?

Normal body weight if the baby = 29.6lb (pounds)

Weight of baby die to fever and diarrhea = 25.2lb(pounds)

Weight loss due to diarrhea and fever :

(29.6 - 25.2)lb = 4.4 lb

Amount of fluid needed to be replaced in litres = weight loss due to sickness

Then we need to convert 4.4lbs to Litre (L)

1 pound (lb) = 0.45359 liter (l)

4.4 lb = (4.4 * 0.45359) L

= 1.995796 L

= 2L

Examine the label information on the packages of a variety of breakfast cereals. Which types of cereals provide the best sources of carbohydrates, lipids, proteins, vitamins, and minerals? Which major nutrients are lacking in these cereals?

Answers

Answer:

B

Explanation:

B

Can You Explain it?
Using your textbook page 5 read the context and predict how do you think tomato plants detect pests on a neighboring plant so
they can protect themselves from infestation? Write your prediction in the box below and in your Evidence Notebook.

Answers

Explanation:

Here is my answer from the textbook :)

Answer:

I know that some plants release certain chemicals, taste terrible to pests like the caterpillar, and alert other plants that there are pests around. As a result of this, when other plants detect the chemical released, they work together towards a solution.

How do you define professionalism

Answers

Answer:

The conduct ,aims or qualities that characterize or mark a profession or a professional person is known as professionalism.

Explanation:

Hope it helps.

Which cube has a higher surface-area-to-volume ratio?

Answers

Answer:

bottom right ....................

Answer:

4 cm x 4 cm x 4 cm..... .

Explanation:

...

Why must seafood be consumed with caution?
Seafood must be consumed with caution because some fish live in polluted water and _____ A. some people are allergic B, some people are unfamiliar with fish C. some people dislike fish

Answers

A. Some people are allergic

Seafood allergies are deadly

Answer:

first blank: some fish live in polluted water

Second blank: some people are allergic to fish

Explanation:

Plato answer

for edmentum

An experiment was performed to measure the growth of bacterial colonies on an agar plate over a 48- hour period. Which type of graph or chart would be most suitable to represent the data. PLEASE HELP! THE ANSWER CHOICES ARE A: Pie chart B: Bar graph C: Stacked bar graph D: Line graph! This is 8th-grade science help:C

Answers

Answer:

D. Line graph

Explanation:

A line graph is used to track changes over short or long periods of time

the other options don’t make sense other than the bar graph but you are not comparing anything and it just makes more sense to use a line graph.

What is the relationship between combustion and plants? (Using the picture)

HELP ILL MARK YOU BRAINLIEST

Answers

During photosynthesis, plants use carbon dioxide and produce oxygen. During metabolism oxygen is used and carbon dioxide is a product. Humans impact the carbon cycle during the combustion of any type of fossil fuel, which may include oil, coal, or natural gas

What are the three most common types of
bond?

Answers

Answer:

The three most common types of bonds are: covalent, ionic, and hydrogen bonds. Hope this helps!

Explanation:

Answer:

U.S. Treasury ,municipal ,and corporate

why is still water an ideal enviroment for mold and cast fossils​

Answers

Answer:

Sediment builds up over organisms.

Explanation:

Answer:

Sediment builds up over organisms.

Explanation:

i got it correct on edge nuity

How is Twain effective at using humor? Cite evidence of humorous moments in the text. Also consider Twain’s intent and viewpoint in your response.

Answers

Twain is effective at using his humor because he uses it to entertain his readers. It makes his readers laugh and provides social criticism mixed with humor. Twain shows the dark side of human nature in a funny way and expresses a serious viewpoint through silly characters.

Humor is the use of words, actions or signals which elicit laughter or smiles in a good natured way from people.

There are different scenarios where humor can be used effectively such as:

To bring relief to a tense atmosphere To make a room more livelyTo bring happiness to a person, etc

With all these in mind, Twain could have been effective at using humor because he knew just the right moment to be humorous and he was able to say the right things at the right time.

Please note that your question is incomplete, and as a result, i gave you a general overview to help you get the right answer.

Read more here:

https://brainly.com/question/14044151

What is a well-known issue with cross-sectional methodology?

Answers

Answer:

This methodology enables to measure simultaneously both the result and exposure in the group under study

Explanation:

A cross-sectional method is a type of scientific design based on observational data. The cross-sectional studies involve the use of diverse groups that differ in the variable investigated but share other features (for example, individuals with the same educational background, ethnicity, economic status, etc). This class of studies is generally used in developmental psychology.

what are some adaptations that help animals who live in the alpine biome survive

Answers

alpine animals adapt to the cold by hibernating, migrating to warmer areas, or insulating their bodies with layers of fat and fur. Their bodies tend to have shorter legs, tails, and ears, in order to reduce heat loss.

Hii!! The correct answer is: They hibernate, migrate to warmer areas, insulate their bodies with fat and fur, and tend to have shorter legs, tails, and ears in order to reduce heat loss. (:

The following question's answers are:

Describe the weather conditions that characterize the chaparral biome.

hot and dry summers

mild winters

most rain comes in winter

Which of the following changes in deciduous forests occurs in the spring?
A. Trees regain their leaves.
b. Trees block the flow of water and nutrients to their leaves.
C.The leaves of trees begin to lose their chlorophyll.
d. Trees live off of stored nutrients.

Answers

A. Trees regain their leaves

Answer:

A. trees regain their leaves.

Explanation:

edge 2020

Which cranial bone can be seen laterally, inferiorly, superiorly when the skullcap is off, and through the orbits of the eye?

Answers

The sphenoid bone.

Though double check

Which of them is important in endurance race physical strength or emotional strength?

Answers

Answer:

Both

Explanation:

Endurance deals with how long you can do something that puts a physical strain on your body and not necessarily how much strain at once. That being said both physical strength and emotional strength play a big role in this. Physical strength is needed to be able to exert yourself and accomplish the initial task in the first place. While emotional strength is also needed in order to not give up and persevere as long as possible. Without will power (emotional strength) you will give up as soon as you are given the opportunity.

Meter is called a standard unit.Give reason.​

Answers

Answer:

The meter is not called a fundamental unit, except informally by some people. In the International System of units (SI), the meter is one of seven base units. Base units can be defined in terms that do not depend on no units beyond other base units or natural constants (e.g., the speed of light). Using no more than those seven base units, other units can be defined and those are called derived units. No factors or coefficients other than one are used to show how they relate to each other

hope it helps :)

please mark it the brainliest!

D)
solid to liquid
Which example shows how a consumer gets energy from food?
A)
a worm eating a dead leaf
B)
a frog laying out in the sun
a rabbit matin

Answers

Answer:

A.

Explanation:

a worm eating a dead leaf, this shows the life process of feeding. Feeding is simply an organism obtainig energy from food. Give me brainliest if i helped!♡

Enzymes are proteins that speed up reactions by

Answers

Answer:

lowering the activation energy needed for the reaction to start

Answer:

lowering the amount of energy required

Explanation:

Plants play a crucial role in the carbon cycle because they A do not release carbon dioxide during cellular respiration. B allow carbon to enter an ecosystem through photosynthesis. C have special bacteria that live in their root systems. D release water into the atmosphere through transpiration. Group of answer choices

Answers

B allow carbon to enter an ecosystem through photosynthesis.

D release water into the atmosphere through transpiration.

A substance in which other substances dissolve is called a solute. true or false

Answers

Explanation:

Hey there!

The answer is false.

Because, Those substances in which other substances dissolve are called solvent.

And those substances which dissolves in solvent are called solute.

Hope it helps...

The relative concentration of each in the plasma membrane is partly regulated by the:_______

Answers

Answer:

ion channels

Explanation:

The plasma membrane plays a critical role in regulating and maintaining ionic potential inside the cell, relative to ionic concentration present outside the cell. The ion channels are specific, in that they only recognize and allow particular ions to pass through and block the rest. Their opening and closing depends on the ionic potential during that time period.

a medical reasearcher is testing a new experimental drug for a headache patients Group A consists of 100 participants who are given the new exprimental drug group B consists of 100 participants who are given a placebo or fake pill. Neither group knows which treatment they received Which is the control group?

Answers

Answer:

Group B... (the Placebo)

Explanation:

I say group B because the medical reasearchers are using group B to see the outcome and effects of the experimtal drug that they gave group A. So if in the end group A (given the experimental drug) has a better response to the headache after taking the pill then group B (given a fake drug) the medical reasearcher will know the effectiveness of the new drug.

Tessa conducted a demonstration about the movement of materials in and out of cells. She closed the door to her classroom, then sprayed a little perfume in the corner of the room. She drew this diagram to represent the room, with the dots representing the perfume molecules. Which statement best describes what Tessa should tell the class about the diagram? Diffusion has already occurred. Diffusion will occur. Active transport has already occurred. Active transport will occur.

Answers

Answer:

Diffusion has already occurred.

Explanation:

Answer:

diffusion has already occured

Explanation:

i took the ed test

In a fluorescence recovery after photobleaching (FRAP) experiment, a fluorescently tagged membrane protein, A, shows very little recovery of fluorescence ten minutes after photobleaching, while membrane protein B shows a rapid increase in fluorescence after bleaching, recovering nearly 80% of its original fluorescent signal by ten minutes. Based on this information, which of the following statements can be made?
A. Proteins A and B interact with each other in a complex
B. Protein A is easily denatured,
C. Protein Bis diffusing in a more fluid membrane.
D. Protein Ahas faster mobility in the membrane.

Answers

Answer:

The correct answer is option C.  Protein Bis diffusing in a more fluid membrane.

Explanation:

Fluorescence recovery after photobleaching or FRAP is a technique used to examine the portability of fluorescent particles with the help of fluorescence microscopy that have been utilized since the mid-70s to evaluate the dispersion or movements of molecules in the cell membranes of the cell.

Fluorescence Recovery After Photobleaching (FRAP) is a strategy for deciding the energy of dispersion in living cells (typically) utilizing fluorescence microscopy.

In the given experiment:

The diffusion coefficient of GFP vary, based on the localization of the protein

Protein B is freely diffusing, due to which recovery is very high compared to protein A.

Protein which is less diffusing shows a slower and less rate of recovery.

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