What are MAD (mitotic arrest deficient) proteins and when are they important in the cell cycle?

Answers

Answer 1

Answer:

The mitotic arrest deficient protein MAD2B (MAD2L2) is a member of a MAD family of proteins and shows 48% similarity to MAD2 (MAD2L1) [1], [2]. Both MAD2 and MAD2B can bind to the anaphase promoting complex or cyclosome (APC/C), which is a downstream target of the mitotic spindle checkpoint.

Answer 2

MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.

The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.

A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.

The checkpoints during mitosis are:

At the end of stage G1 and before S.

Before anaphase in mitosis.

DNA damage checkpoints in G1, S or G2.

The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.

That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.

Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.

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Related Questions

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Is light an essential condition for germination ?
why or why not ?

gamsahamnida ​

Answers

Answer:

No

Explanation:

Conditions necessary for germination are :

Temperature/Warmth

Oxygen/Air

Water/Moisture

(ii) Two grey mice, when mated, produced a total of 8 white, 9 black and 17 grey offspring. Student A suggested that grey coat colour was dominant in the mice. Student B strongly disagreed Which student is right? Explain your answer using appropriate symbols (4 marks)​

Answers

Answer: Grey color is the dominant color in this case because both parents are what color so they pass that on to the offspring and there where more grey offspring then any other

As a part of her homework, June make a flowchart about the steps involved in hearing the sound energy produced by wind chimes.

A flowchart with four steps. The first step is the rods vibrate back and forth. The second step is wind chime rods hit each other. The third step is sound waves are created. The fourth step is the sound travels into your ears.

Which statement best explains the error in June's flowchart?

The wind chime rods hit each other before they begin to vibrate.
Sound waves are created before the wind chime rods hit each other.
The sound of the wind chimes travels to your ear before the rods vibrate.
The spin of the rods causes sound energy, not its vibrations.

Answers

Answer:

A is the final answer........

kyle has a cancer of the lymph nodes or glands. what type of cancer does kyle have?

Answers

it’s lymphoma cancer

What processes have destroyed most of the remnants of earths earliest formation

Answers

Answer:

volcanic eruptions

Explanation:

If a true-breeding tall pea plant is crossed with a true-breeding dwarf pea plant and all of the offspring are tall plants, the trait tall plant is:

Answers

Answer:

It is dominant over "dwarf plant."

Explanation:

If a true-breeding tall pea plant is crossed with a true-breeding dwarf pea plant and all of the offspring are tall plants, the trait tall plant is it is dominant over "dwarf plant."

What is dominant traits?

Dominant traits are always explained when the related allele has dominant, even if only one copy of the dominant trait exists. Recessive traits are expressed only if both the connected alleles are recessive.

The frequency of expression of dominant and recessive traits can be Dominant traits = always / Recessive = sometimes.

According to the question if there is self cross TT×tt then there is TT, Tt, Tt and tt, which means there is a 75% possibility of dominant trait and 25% recessive.

A dominant trait has an inherited trait or characteristic that appears in an offspring and covers the effects of another allele and/or prevails or exhibit its trait above another.

Therefore, If a true-breeding tall pea plant is crossed with a true-breeding dwarf pea plant and all of the offspring are tall plants, the trait tall plant is it is dominant over "dwarf plant."

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After you finish a big meal, the level of glucose in your bloodstream increases. What happens next in order for your body to process the glucose

Answers

Answer:

Digestion

Explanation:

The body digest the food down through the mouth to the anus

some enzymes also act on the food for easy digestion

If the alleles of two different genes are present on the same chromosome, the closer they are to each other the more likely they are to ________________________________ during gamete production.

Answers

If two alleles of different genes are in close proximity with each other on the

same chromosome, they would most likely link during gamete production.

Meiosis is the type of cell division that takes place in gamete( sperm and egg cells) production. The alleles are responsible for the phenotype of an

organism.

When alleles are in close contact on the same chromosome they are most

likely to be linked together and transmitted as a single unit . These brings

about variation between parents and daughter cells in some features such

as color, height etc

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An ocean pH change from 8.2 to 8.0 is NOT significant as the .2 change is very small.

Answers

So far, the ocean's pH has dropped from about 8.2 in preindustrial times to around 8.05. This seemingly small change may already be affecting ocean organisms and future CO2 emissions could lower ocean pH even further

Which membrane component is a glycoprotein?
ОА
ОD
ОB
ОC

Answers

OA

Carbohydrates. Carbohydrates are the third major component of plasma membranes. In general, they are found on the outside surface of cells and are bound either to proteins (forming glycoproteins) or to lipids (forming glycolipids).

OA, hope that helped!!

Which of the following are forms of cell regulation?

Answers

Answer:

the answer is should be C

I c would be correct

glial cells that surround the neurons in ganglia are:

Answers

Answer:

Explanation:

Satellite cells are small glia that surround neurons' sensory ganglia in the ANS. These resemble the astrocytes of the CNS and assist in regulating the external chemical environment. PNS satellite glia are very sensitive to injury and may exacerbate pathological pain.

Glial cells surrounding the neurons of neurons are satellite cells.

What are the functions of glial cells?

Glial cells are a type of cell that provide physical and chemical support to neurons and maintain their environment. Located in the central nervous system and peripheral nervous system.

Glial cells outnumber neurons in the brain and outnumber them by a ratio of 3:1. Although glial cells also have complex processes extending from their cell bodies, they are generally smaller than neurons and  lack axons and dendrites.

Oligodendrocytes form the myelin sheath around axons. Astrocytes supply neurons with nutrients, maintain their extracellular environment and provide structural support. Microglia clear pathogens and dead cells.

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how might differences in enzyme concentrations affect rates of photosynthesis and respiration?

Answers

Answer:

enzymes are biological catalysts which speed up the rate of biochemical reactions

Increasing the concentration of enzymes would speed up the rate of photosynthesis and respiration due to the fact that the enzyme substrate complex can occur on a much larger scale i.e. more enzymes would be able to bind with more substrates producing more Oxygen in the case of photosynthesis and more ATP in respiration

Decreasing the concentration of enzymes would have the opposite effects

The differences in enzyme concentrations affect rates of photosynthesis and respiration are process accelerators.

What enzymes are involved in photosynthesis?

Enzymes such as Rubisco, sedoheptulose-1,7-bisphosphatase, aldolase and transketolase dominate the control of photosynthesis. Reductive fixation of CO2 requires ATP and NADPH and their concentrations in the stroma increase when chloroplasts are illuminated.

The chemical reactions involved in photosynthesis are controlled by enzymes . The temperature increases the number of collisions increases, therefore the rate of photosynthesis increases. However, at high temperatures, enzymes are denatured and this will decrease the rate of photosynthesis.

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the atmosphere of earth is comprised mostly of oxygen and

Answers

Answer:

Nitrogen

Explanation:

The air in the atmosphere is made out of 78% Nitrogen, 21% oxygen, and 1% other gases.

What are the two principle forms of ossification that occur in the development of the skeletal system

Answers

Answer:

Ossification is a process in which the mesenchymal cells and cartilages convert to bone during development. it is has two types: Membranous and endochondral ossifications. It occurs in mesenchyme which has formed a membranous sheath (figure 4) .

Why don't animal cells need chloroplasts? Question 4 options: Animals do not make their own food. Animal cells make their own chlorophyll. Animal cells collect sunlight another way. Animals use photosynthesis to make their own food.

Answers

Animals do not make their own food.

Animals don’t make their own food

find out how fermented bean pastes are made and write about the biotechnology of this useful food​

Answers

Answer:

Altogether, this recipe takes about five days and is done in three stages: Soaking the beans for 1-2 days. Cooking the beans until soft, about 1-2 hours. Mixing with seasoning and lacto-bacilli and allowing to ferment for 3 more days.

Modern Biotechnology is helpful in enhancing taste, yield, shell life and nutritive values.

Explanation:

I HOPE ITS HELP YOU

Foods or beverages created through managed microbial growth and enzymatic conversion of food components are referred to as fermented foods.

What is biotechnology?

Biotechnology is the application of biology to the problem-solving and product-making processes. The most well-known application of biotechnology is the use of genetic engineering to produce therapeutic proteins and other medications.

Because the production of antimicrobial metabolites (such as organic acids, ethanol, and bacteriocins) lowers the danger of contamination with pathogenic bacteria, food fermentation has historically been used as a preservation technique.

Therefore, Foods or beverages created through managed microbial growth and enzymatic conversion of food components are referred to as fermented foods.

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By which time period did the average
temperature across Earth's surface rise
1.62 degrees F above the 20th century
average, the hottest period in the 136-
year average?
A. 1300s
B. 1500s
C. 1700s
D. 2000s

Answers

Answer:

C. 1700s

Explanation:

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Answer:

C. 1700s

Explanation:

How has the average temperature on Earth changed over time?

Earth's temperature has risen by 0.14° F (0.08° C) per decade since 1880, and the rate of warming over the past 40 years is more than twice that: 0.32° F (0.18° C) per decade since 1981. ... From 1900 to 1980 a new temperature record was set on average every 13.5 years; from 1981–2019, a new record was set every 3 years.

The release of one phosphate group from ATP powers the reactants in the cell which phosphate is the one that is released from ATP

Answers

Answer:

ADP

Explanation:

Your question: The release of one phosphate group from ATP powers the reactants in the cell which phosphate is the one that is released from ATP

My answer: ADP

Why is my answer correct?

If a cell needs to spend energy to accomplish a task, the ATP molecule splits off one of its three phosphates, becoming ADP (Adenosine di-phosphate) + phosphate. The energy holding that phosphate molecule is now released and available to do work for the cell.

Hope this helps! :)

Help me with this please

Answers

Answer:

4.Red

5. gamma waves

5. Gamma waves

Explanation:

if you look at the visible light they label all the colors for you red is at the end closest to increasing wavelength

Dan has a very large kidney stone that is not passing on its own. Which of the following may the doctor utilize?

Answers

Answer:

d. Any of the above

Explanation: is correct/post protected

when do alleles for two different genes—located in two different chromosomes—segregate?

Answers

Meiosis is the answer

pls help asap I'll mark brainliest​

Answers

Answer:

water then carbon diaxide  and oxygen

Explanation:

Answer:

Light energy + Water + Carbon Dioxide to leaf to sugar + Oxygen

Explanation:

This is called photosynthesis. Hope it helps

altering the environment to minimize the stimuli for eating is called

Answers

Answer:

Stimulus control

Explanation:

You are controlling the stimuli. Altering the environment to influence, in this case minimize, stimuli is an example of stimulus control.

1. Will loves to go fishing in the coastal estuary. He brings home his catch every weekend and bakes the fish for dinner. The next time he goes to his favorite fishing area, a sign is in place, warning residents of high heavy metals in the water. Which statement best explains the impact of eating fish from the estuary?
Heavy metals can biomagnify in large fish, making human consumers ill.
Heavy metals are water soluble; humans can eat them in small amounts.
Large fish will die from the heavy metals, but small fish can be consumed.
Will should avoid small fish but can collect large fish with less heavy metals.

2. fisherman collecting shellfish notices that many are very small and lack the thick hard shell he is accustomed to seeing in the species. Which statement best explains what may be impacting the shellfish population?

Ocean acidification
Ocean warming
Coral bleaching
Climate change

Answers

Answer:

Ocean Acidification

Explanation:

The high level of acid in the ocean has caused the shellfishes shell to wear down.

If you study and specialize in chemical processes, you might be a __________.

If you are in charge of sketching the design for a new product, you might be a _______.

If you are interested in operating biotechnology equipment, you are most likely interested in becoming ___________.

If you have dreams of working in the field, collecting samples, and putting together data, you are most likely interested in becoming a _____________.

Answers

Answer:

Biochemists and biophysicists

bioengineer

biotechnology technician

biotechnology researcher

Explanation:

Think about how you obtain the energy you need to do everyday activities like doing chores, going to school, or playing sports. Write about it in the box below.

Answers

Answer:

I get energy by sleeping at night and eating at least 3 meals a day everyday.

Explanation:

How do the properties of lipids
help explain the structure of a cell membrane?

Answers

Explanation:

Lipids give cells membranes a flexible structure which forms a strong barrier between the cell and its surroundings

Answer:

Lipids give cells membranes a flexible structure which forms a strong barrier between the cell and its surroundings. This tells us that the lipid surrounds the structure which then forms the shape of the cell.

Explanation:

All members of a species living in the same location are called a


population


genus


community


ecosystem

Answers

Answer:

population is the best answer

When more than two species are interacting, and evolutionary change in one causes change in one or more of the others, it is known as:

Answers

Answer:

coevolution, the process of reciprocal evolutionary change that occurs between pairs of species or among groups of species as they interact with one another. The activity of each species that participates in the interaction applies selection pressure on the others.

Explanation:

Hope I could help.

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