Which essential molecule in the body is out of equilibrium because of a cftr gene defect?.

Answers

Answer 1

Mutations in the gene that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein lead to cystic fibrosis.

Cystic fibrosis is brought on by mutations, or mistakes, in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which either prevent the production of any CFTR protein or cause it to be malformed and unable to carry out its essential cellular role.

The deletion of phenylalanine 508 (F508del) in the cystic fibrosis transmembrane conductance regulator is a mutation that has been linked to the disease (CFTR). The CFTR's first nucleotide-binding domain (NBD) contains the amino acid. Gating issues and faulty channel processing result from this mutation.

CFTR is a complex protein that is present on the cell surface membrane in a number of tissues and serves as a controlled chloride ion channel. On the apical membrane of the cells lining the airways in the lung, CFTR is present.

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Related Questions

micro which of the following methods of action would be bacteriostatic? a) competitive inhibition with folic acid synthesis b) inhibition of protein synthesis c) injury to plasma membrane d) inhibition of cell wall synthesis e) competitive inhibition with dna gyrase

Answers

Bacteriostatic action would be inhibited protein synthesis.

A bacteriostatic agent, also known as a bacteriostat, is a biological or chemical agent that prevents bacteria from reproducing while not necessarily killing them. Bacteriostatic antibiotics, disinfectants, antiseptics, and preservatives can be distinguished based on their application. Bacteriocidal methods include heat, filtration, radiation, and chemical exposure. Heat sterilisation is a widely used method in microbiology laboratories.

Microorganisms such as bacteria, fungi, and yeast are incinerated by the dry heat of an open flame. Tetracyclines and gly-cylcyclines, chloramphenicol, macrolides and ketolides, lincosamides, streptogramins ,oxazolidinones, and aminocyclitols are bacteriostatic protein-synthesis inhibitors that target the ribosome. Bacteriostatic antibiotics inhibit bacterial growth by interfering with protein production, DNA replication, and other aspects of bacterial cellular metabolism.

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Chains of nucleic acids have directionality and are read in a certain way just like languages are read from "left to right" or "right to left."
dna is always read in the___direction, whereas rna is read in the____direction.

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DNA is always read in the direction 3' to 5', whereas RNA is read in the 5' to 3' direction.

RNA polymerase are responsible for synthesizing RNA strand complementary to a template DNA strand. They use to synthesizes the RNA strand in the 5' to 3' direction, while reading the template DNA strand in the 3' to 5' direction.

On the other hand DNA is always synthesized in the 5'-to-3' direction, That means that nucleotides are added only to the 3' end of the growing strand. 5'-phosphate group of the new nucleotide binds to the 3'-OH group of the last nucleotide of the growing strand.

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Describe three ways that communities can conserve their freshwater resources.

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The freshwater needs of both people and ecosystems are to practice water conservation.

What are one-way humans can conserve freshwater?

freshwater recycles plastics, glass, metals, and paper. Buy recyclable products rather than throw-aways, as it takes water to make almost all. Turn off the tap while stroking your teeth and washing the dishes. Shave a minute or two off your shower time.

Farmers can play a main role in water management by using a water conservancy method for irrigation known as drip irrigation. In this technique, plants are watered using small tubes, and this water is directly brought to the base of the plant.

So we can conclude that The most practical solution is reusing and recycling freshwater.

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Answer:

They say:

Educate to change consumption and lifestyles.Invent new water conservation technologies.Recycle wastewater.Improve irrigation and agricultural practices.Appropriately priced water.Develop energy-efficient desalination plants.Improve water catchment and harvesting.

which three elements are common to the reactants and the products of both photosynthesis and cellular respiration?

Answers

Hydrogen, oxygen, and carbon.

What are the components of photosynthesis and cellular respiration and what are their byproducts?

In cellular respiration, the products and reactants for photosynthesis are switched around: Carbon dioxide and water, which are byproducts of cellular respiration, are the reactants in photosynthesis. Oxygen and sugar, byproducts of photosynthesis, are the reactants of cellular respiration.

What are the similarities between photosynthesis and cellular respiration?

The majority of life on Earth depends on two biological processes: photosynthesis and cellular respiration. Both of these processes utilize a number of similar chemicals, including oxygen (O2), carbon dioxide (CO2), water (H2O), glucose (C6H12O6), and adenosine triphosphate, as well as other complex steps (ATP).

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A group of organisms that can breed and produce fertile offspring is known as a ...

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A group of organisms that can breed and produce fertile offspring is known as a species.

A species, according to the most widely used definition, is a group of organisms that can potentially interbreed, or mate, with one another to produce viable, fertile offspring. A group of organisms must produce healthy, fertile offspring when they interbreed in order to be considered a single species in the biological species concept. In some cases, organisms from different species can mate and have healthy offspring, but the offspring are infertile and unable to reproduce.

For example, when a female horse and a male donkey mate, they produce hybrid offspring known as mules. Although a mule is perfectly healthy and can live a long life, it is infertile and cannot have its own offspring. As a result, we regard horses and donkeys as distinct species.

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Where is the center of the anatomic origin of the anterior talofibular ligament on the fibula?.

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The lateral malleolus' anterior edge is where the anterior talofibular ligament begins. According to measurements made along the fibula's axis, the center is typically 10 mm distant from the tip [10].

The ATFL and CFL's fibular origins were found on the anterior fibula border, respectively 10–13.8 and 5.3–8.5 mm proximal to the fibula's tip. The talar insertion of the ATFL was situated 11.3–14.8 mm from the anterolateral corner of the talar body or 14.2-18.1 mm from the subtalar joint.

The anterior talofibular ligament is the ankle's weakest and most frequently injured ligament. This ligament is a lateral one, which implies that it is made up of a band of connective tissue.

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which of these is a cash crop?

A. Latex

B. Cucumbers

C. Grass

D. Strawberries

Answers

Answer:

a latex

Explanation:

you could just look it up

Answer:

A. Latex

Explanation:

because all can be eaten(food crops )except latex

explain why lithium mixed with potassium is stronger than pure lithium

Answers

Lithium when mixed with potassium is stronger than pure lithium because the tendency to lose electrons is greater in potassium than that in lithium.

The reason behind this phenomenon is that potassium contains more loosely bonded valence electrons in comparison with lithium alone. If we talk about more direct reactions, potassium reacts more aggressively than lithium alone. The outer electron of potassium is far away from the positive magnetism of the nucleus in comparison to lithium so potassium show high reactivity.

Another reason to sum up potassium in front of lithium is that its ionizing enthalpy (amount of energy to remove an electron from an isolated gaseous atom in its gaseous state) is minimum in comparison to lithium.

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which one of the options by itself does not possess the ability to synthesize its own proteins?
a. a virusb. a human cell, a virus, and a bacterial cellc. a viral particle and a bacterial celld. a human celle. a bacterial cell

Answers

The option that does not possess the ability to synthesize its own protein is: a virus.

Proteins are the biomolecules that are necessary for the living body to perform multiple functions. A protein is polymers made up of amino acid monomers. The functions that proteins can perform are varying like: signaling, enzymatic, transport, structural, etc.

Viruses are the acellular components. They are called acellular because they do not follow the cell theory. Viruses do not function outside any living body. However once inside any living host, they exhibit the potential to takeover the machinery of the cell they are present in and synthesize their own viral particles or proteins.

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The current level of folic acid fortification of grain products leads to an intake of about 100 extra micrograms of folic acid per day. Why doesn’t the fortification program mandate higher levels of folic acid to more effectively meet requirements?.

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The amount of folic acid added to grain products at this time results in an additional daily consumption of roughly 100 micrograms. Because too much folic acid might conceal a vitamin B-12 deficiency, the fortification programme does not need greater doses of folic acid.

Malabsorption of food-bound vitamin B12 is the most frequent cause of vitamin B12 deficiencyin elderly individuals. Therefore, it is advised that the 2.4 microg/d recommended daily requirement be predominantly reached by crystalline vitamin B12, which is thought to be well absorbed in people with food-bound malabsorption.

There is worry that increased folic acid intakes from fortified foods and nutritional supplements might conceal the macrocytic anaemia caused by vitamin B12 deficiency, obviating a crucial diagnostic indicator.

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the goal of psychodynamic therapy is to help the client become aware of conflicts that may be creating problems for them.

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The goals of psychodynamic therapy are client self-awareness and understanding of the influence of the past on present behavior.

Primary goal of psychodynamic psychotherapy is to make the unconscious in to conscious state. During the psychodynamic session, the therapist reads a word aloud and the patient responds with the first word that comes into his mind.

Psychodynamic therapy, therapists help people survey emotions, thoughts, early life experiences and beliefs to gain insight into their lives and the problems that they are dealing presently .They also gain knowledge about the psychological patterns they have developed over time.

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What were two factors that contributed to the end of the open range on the western frontier?

Answers

Answer: Barbed wire and windmills.

Explanation: Barbed wire and windmills brought about the closing of the once open range, ended the great trail driving era, and allowed ranchers to improve their land.

ocean waters have a varying carrying capacity for phytoplankton and other organisms that perform photosynthesis. the carrying capacity is very high near the surface, and then decreases with depth. it is zero in the deepest ocean waters. which statement about the water is most useful for explaining this variation?

Answers

Brightness decreases with depth is the correct statement which explains the variation in ocean waters with varying capacity for phytoplankton and other organisms to perform photosynthesis. The correct option to this question is B.

Photosynthesis, which takes place in sunshine, is the first step in almost all food chains. As a result, marine plants will only grow close to the surface where there is access to light. Of course, this will keep herbivores and their predators at the surface as well.Because sunlight can only permeate the water environment to a depth of 50 to 100 m in oceanic water bodies, phytoplankton are only found there. Photosynthesis depends on sunshine. Mineral nutrients are also important for growth, with land providing the most.

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Complete question: Ocean waters have a varying carrying capacity for phytoplankton and other organism that perform photosynthesis. the carrying capacity is very high near the surface, and then decreases with depth. it is zero in the deepest waters. Which statement about the water is MOST useful for explaining this variation.

A.) temperature decreases with depth.

B.) Brightness decreases with depth.

C.) Salinity increases with depth.

D.)Dissolved carbon dioxide decreases with depth.

E.) Dissolved carbon dioxide increases with depth.

Telescopes that use lenses for focusing light are called ____ telescopes.

please help ASAP

Answers

Refracting Telescopes
Refraction telescopes

The term "cell" emerged in biology because, under early microscopes, cells looked like rooms monks slept in at a monastery.
O
O b
a
False
True

Answers

It is true that the term "cell" originated in biology since early microscopes showed that cells resembled monks' dormitories.

Robert Hooke examined a thinly cut piece of cork under a crude microscope. He noticed a group of walled boxes that resembled the monks' little quarters, or cellula. The cell has a long and fascinating history that ultimately paved the path for many of the modern scientific breakthroughs.

What kind of muscle tissue has fibers that lock together?

Adjacent cardiac muscle fibers' membranes touch and intertwine. Through the gap junctions, the impulse can travel directly from one cell to another. Because of this, cardiac muscle fibers can coordinate rhythmic contractions without individual innervation.

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Compare and contrast local anesthetics, some general anesthetics, and botulinum neurotoxin in terms of the effect they have on neuron excitability and function

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Local block on the postsynaptic side generally just blocks all channels botulinum doesn't affect action potential but does affect what goes through the cell.

Local anesthetics stop nerves in parts of the body that send signals to the brain. You won't feel any pain after the local anesthesia, but you may feel some pressure or movement. It usually takes only a few minutes for the area where the local anesthetic is administered to lose sensation.

Local anesthetics such as novocaine block neurotransmission to pain centers in the central nervous system by binding to and inhibiting the function of ion channels in the cell membranes of nerve cells called sodium channels. Local anesthetics can block the transmission of nerve impulses along all types of nerve fibers.

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Describe five ways in which you unnecessarily waste energy during a typical day.

Answers

Answer:

1/ Leaving the Lights On

2/ Leaving electronics plug

3/ Forgot to close Refrigerator

4/ Forgot to shut the water

5/ Washing Clothes in Hot Water

Explanation: There are a lot more ways, but this is the most common I see in my life!

What type of body symmetry do animals in phyla Platyhelminthes, Annelida, and Nematoda have?
-bilateral symmetry
-radial symmetry
-asymmetry and radial symmetry
-asymmetry

Answers

Phyla Platyhelminthes, Annelida, and Nematoda have bilateral symmetry.

What is  symmetry?

A property of some organisms in biology known as symmetry is the uniformity of parts on a plane or around an axis. A symmetrical creature would have an even distribution of duplicate parts on either side of the axis (indicating symmetry). It could not be an exact replica but rather a close repetition. Bilateral symmetry is an illustration of symmetry in living things.

What is bilateral symmetry?

A type of symmetry in which the opposing sides are similar is known as bilateral symmetry. In a sagittal plane, the outside look is identical on the left and right sides (such as the body plan of most animals, including humans). An organism's body plan can be divided into equal mirror halves in the sagittal plane when it exhibits bilateral symmetry. Organs and other internal body parts may not always be symmetrical. Animals that have bilateral symmetry belong to the taxonomic group Bilaterian. These animals, which are also known as bilaterians, have left and right sides to set them apart from species with other types of symmetry (such as radial symmetry) and those without symmetry (asymmetry).

Hence, Phyla Platyhelminthes, Annelida, and Nematoda have bilateral symmetry.

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Using this information describe one contribution of each of the following to ATP synthesis:

a. Catabolism of glucose in glycolysis and pyruvate oxidation.


b. Oxidation of intermediates in the Kreb's cycle


c. Formation of a proton gradient by the electron transport chain

Answers

a. Catabolism of glucose in glycolysis and pyruvate oxidation - Produces NADH that is used in the ETC.

b. Oxidation of intermediates in the Krebs Cycle - Produces NADH or FADH2 for use in the ETC.

c. Formation of a proton gradient by the electron transport chain- The flow of protons through membrane bound ATP synthase generates ATP

What is ETC ?

The electron transport chain (ETC) and chemiosmosis are the two processes that make up oxidative phosphorylation. The ETC is made up of a group of proteins that are affixed to the inner mitochondrial membrane and organic molecules that allow electrons to pass through and release energy through a series of redox processes.

An electron transport chain (ETC) is a collection of protein complexes and other molecules that associate protons (H+ ions) with the movement of electrons from electron donors to electron acceptors through redox processes (both reduction and oxidation occur simultaneously).

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What is the function/job of the digestive and respiratory systems?

Answers

Answer: The digestive system is responsible for breaking down food and absorbing nutrients from it, while the respiratory system is responsible for bringing oxygen into the body and removing carbon dioxide.

Explanation:

The digestive system consists of a number of organs that work together to process food and extract nutrients from it. These organs include the mouth, esophagus, stomach, small intestine, large intestine, and rectum. The digestive system starts with the mouth, where food is mechanically broken down by chewing and mixed with saliva, which contains enzymes that begin the process of breaking down food. The food is then swallowed and passes through the esophagus, which moves it to the stomach, where it is mixed with stomach acid and enzymes that continue the process of breaking down the food. The partially digested food is then moved to the small intestine, where it is further broken down and the nutrients are absorbed into the bloodstream. The remaining indigestible material is moved to the large intestine, where water is absorbed and the material is eliminated through the rectum.

The respiratory system consists of the nose, mouth, pharynx, larynx, trachea, bronchi, and lungs. When we inhale, air passes through the nose or mouth, down the pharynx and larynx, and into the trachea. The trachea then splits into two bronchi, which lead to the left and right lungs. The lungs are made up of tiny air sacs called alveoli, where oxygen from the air we inhale is exchanged with carbon dioxide from the body's cells. The oxygen-rich blood is then carried back to the heart, where it is pumped to the rest of the body. When we exhale, the carbon dioxide is expelled from the body.

Since they are small and have a selective advantage over larger plants, stone walls, fences, and cracks in exposed rocks are ideal microhabitats for.

Answers

Mosses are very tiny and they can be a habitat in stone walls, fences, and cracks in exposed rocks which are ideal microhabitats

All around the world, mosses can be found in wet, shaded environments, with the exception of saline water. The species that cover woodland and forest floors are the ones for which they are most known. In terms of ecology, mosses erode exposed substrates, liberating nutrients that later-emerging, more sophisticated plants can utilise. Additionally, they play a crucial role in the nitrogen and water economy of various vegetation types

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Chromosome mutations involve the deletion or duplication of many genes. The effects of chromosome mutations are often much greater than mutations within a single gene, because chromosome mutations.

Answers

Because chromosome mutations can result in improper child development, their effects are frequently far more severe than those of gene mutations. The best choice is B.

A mutation is a change to the DNA sequence of an organism. Errors in DNA replication during cell division, exposure to mutagens, or viral infection can all result in mutations. When a DNA gene is disrupted or altered in such a way that the genetic notification carried out by that gene is altered, mutations occur. A mutagen is a substance that permanently modifies the physical components of a DNA gene, changing the genetic information. Chromosome structural changes have the potential to impair system growth, development, and operation.

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In general, an organism will be more likely to develop phobias of __________. A. Dangers faced during natural circumstancesb. Unnatural modern inventions, like carsc. Easily understood forces and pressuresd. Dangers encountered in dreams and visions.

Answers

An organism is more likely to develop phobias when presented with threats in their environment.

Exists phobophobia?

The fear of being terrified is phobia. You may be afraid of the bodily signs of fear or concerned that you might acquire a phobia. Many individuals who suffer from phobias also have additional phobias or mental health issues.

Who is afraid of bananas?

Banana phobia is a rare condition that affects a small number of people worldwide. Most cases start in childhood when a child is forced to eat bananas to the point of experiencing nausea or vomiting by their parents or other caregivers.

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a brown guinea pig is crossed to a cream guinea pig. half the large number of f1 offspring are brown and half are charcoal. what was the genotype of the parents?

Answers

White coat color is a recessive trait in guinea pigs,  genotype  whereas black coat color is a dominant characteristic. when black pigs that are heterozygous are crossed.

Why are cream-colored offspring created when yellow guinea pigs YY and white guinea pigs WW are crossed?

The traits of these two alleles are combined in a heterozygote when they are both present. This is why a yellow and white guinea pig is crossed to produce a cream colored offspring since cream is a combination of yellow and white.

Why did all guinea pigs in the f1 generation have black skin?

The parent guinea pigs are black because the dominant allele for a black coat. But what if one of their descendants carries both of the brown recessive allele.

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explain why cells are so small. Please include the words "surface area to volume ratio."

I just need a small explanation

Answers

Answer:

Explanation:

Cells are small because of the surface area-to-volume ratio. This ratio refers to the relationship between the surface area of an object and its volume. In the case of cells, a smaller size means a greater surface area to volume ratio. This is important because the surface area of a cell is where important biological processes, such as the exchange of oxygen and nutrients, take place. A greater surface area to volume ratio means that these processes can be more efficient, allowing the cell to function properly. Additionally, a smaller size allows cells to be more agile and move more easily within the body. Overall, the small size of cells is important for their function and survival.

Which of the following is true regarding troponin ________?
Question options:

A) it contains two subunits.

B) it is a subunit of the myosin myofilament

C) it is long and flexible

D) it has a binding site for Ca++

E) it has a binding site for ATP

Answers

The correct answer is D) it has a binding site for Ca++

What is Troponin? Proteins called troponins are present in the heart muscles. When the heart is damaged, troponin is released into the bloodstream.Muscle contraction is regulated by troponin proteins. They're divided into three smaller groups.The three troponin proteins are troponin C (TnC), troponin I (TnI), and troponin T (TnT), which hooks the troponin proteins to a different protein called tropomyosin and causes the muscles to contract.Troponin I or TnT levels are determined via testing.The concentration of ttroponin is expressed in nanograms per millilitre (ng/mL). Troponin levels are measured by high-sensitivity testing in nanograms per litre (ng/L).

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what are some of the ways that your choices can affect the way your body self-regulates appetite and satiety via the production of ghrelin and leptin? (choose all that apply)

Answers

A hormone called leptin helps people eat less and lose weight and body fat. If you drastically reduce your calorie intake, your body will create more ghrelin than it should.

Foods that have been processed and labeled as "low-fat" can help you maintain healthy levels of ghrelin and leptin. You will experience hunger and fullness in appetite advantageous ways if you exercise enough. You can keep your ghrelin and leptin levels in check by eating a balanced diet, avoiding processed foods, and exercising regularly. Your body uses leptin primarily to help maintain a stable balance between food intake and energy expenditure (expenditure). Leptin aids in regulating energy balance and suppressing (preventing) appetite.

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Activated helper T-lymphocytes produce cytokines, which may stimulate B-lymphocytes to proliferate and differentiate into plasma cells capable of producing antibodies. TRUE/FALSE

Answers

TRUE : Cytokines produced by activated helper T-lymphocytes may encourage B-lymphocyte proliferation and differentiation into plasma cells capable of generating antibodies.

Which types of cells can produce antibodies?A type of white blood cell called a lymphocyte is a component of the immune system.B cells and T cells are the two primary subtypes of lymphocytes.Antibodies made by B cells are utilized to combat foreign bacteria, viruses, and poisons.After B-lymphocytes differentiate into plasma cells, they begin to generate antibodies.the B lymphocytes To defend your body from a particular invader, the acquired immune system produces special proteins (known as antibodies) with assistance from the innate immune system.After the body has been exposed to the invader, B lymphocytes produce these antibodies.

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you are doing a biochemical analysis of molecules from cells from patients with a certain disease compared to cells from control patients who do not have the disease. you find that patients with the disease have unusually high levels of cytosine molecules with ch3 groups attached to their cells. which modification has taken place in the cells from the disease patients?

Answers

According to DNA methylated bases, the cell alteration linked to differential cytosine methylation on disease patients' DNA is referred to as an epigenetic modification.

What do you understand by epigenetics?

The study of epigenetics, a branch of genetics that focuses on how various chemical alterations to the DNA nucleotide sequence and associated chromatin proteins (histones) may change the expression of particular genes, is crucial for understanding disease states and developmental pathways.

The epigenetic changes, which control gene expression in specialized eukaryotic cells, include DNA methylation organized on CpG islets (cytosine-rich areas), acetylation and/or methylation of histones, non-coding RNA pathways, etc.

The study of how chemical groups added to DNA and/or associated chromatin proteins may change gene expression and hence affect the status and progression of disease is known as epigenetics, according to the findings presented here.

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During the winter, this species of fox has white fur, but in the summer, it has brown fur. what environmental change may have lead to this fox's fur color? snow cover increase in sun’s brightness volcanic eruption global warming

Answers

The Arctic Fox changes to a frostier white colour in the winter, whereas foxes in Canada and Alaska change to a pale white colour during the same season.

In the summer, Arctic Foxes are brownish grey, but in the winter, they become a frosty white tint. Their Canadian and Alaskan brothers, in contrast to the Arctic Fox, have a slightly different color. In the summer, they are slate grey, and in the winter, they only become a slightly paler whiter color.

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Answer: snow cover

Explanation: took the test.  very late answer too.

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