Which of the following best predicts how GSK3β mutations can lead to the development of cancer?

answer choices
Cells with inactive GSK3β fail to trigger apoptosis.
Cells with inactive GSK3β fail to proceed past the G2/M checkpoint.
Cells with overactive GSK3β are more likely to repair DNA damage.
Cells with overactive GSK3β have longer cell cycles.

Answers

Answer 1

Cells with inactive GSK3β fail to trigger apoptosis. So, the correct option is (A).

What is Apoptosis?

Apoptosis is defined as programmed cell death which occurs in multicellular organisms. These biochemical events lead to characteristic cell transformation and death where changes include cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation and mRNA decay.

Tumor cells are able to evade apoptosis which leads to uncontrolled cell proliferation. Glycogen synthase kinase 3 (GSK-3) is a protein kinase which phosphorylates serine and threonine amino acid residues on various substrates, thus activating various signaling pathways and performing various biological functions.

GSK-3-mediated phosphorylation on various substrates can lead to activation or deactivation of apoptosis depending on the cell type. Cells with inactive GSK3β fail to trigger apoptosis, predicting how GSK3β mutations may lead to cancer development.

Thus, cells with inactive GSK3β fail to trigger apoptosis. So, the correct option is (A).

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Related Questions

Bio homework help
pedigrees

Answers

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In the 19th century, the agricultural revolution increased food production while the industrial revolution improved methods of
transporting food and other good additionally, advances in medicine, sanitation and nutrition have decreased the death rates further.
These factors combined to produce the rapid growth of the human population today. Yet other factors impact population demographics:
they include economic, political, religious conditions as well as resource availability.
Consider the demographics for two countries: one with a low-income, almost impoverished population; they other an economically well-off
country. What factors listed would contribute to the decline in birth rate and the larger +75 population in the high income country? Check all
that might apply.
Females have access to educational resources
Better nutrition: increased food supplies and distribution
There has been widespread emigration during the last few decades
Inadequate health care for women during pregnancy and for their babies after birth
A high incidence of infectious disease
Good sanitation and personal hygiene

Answers

Answer:

 A Low Income Impoverished Population could be Uganda and a Economic Well off country could be the Netherlands

Explanation:

Which statement best contrasts the urinary and excretory systems?

The urinary system filters waste for nutrients, while the excretory system has no filter,

The urinary system removes liquid waste, while the excretory system removes solid waste.

The urinary system includes the bladder, while the excretory system does not.

The urinary system is involuntary, while the excretory systenris voluntary.

Answers

Answer:

The urinary system removes liquid waste, while the excretory system removes solid waste.

Explanation:

Yellowstone National Park is located on top of a large active volcano. Heat rising from the underground magma chamber of the volcano fuels unique ecosystems within the park's geysers, hot
springs, and mud spots. If the volcano were to become inactive, the stability of ecosystems in the park's thermal features would
A decrease
B. increase.
С
decrease, then increase
D. increase, then decrease.

Answers

Answer: A

Explanation:

Decrease, Btw if I'm wrong I'm sry lol

But I think it's A

Im pretty sure A, sorry if i get it wrong

the rate of the Earth's and moon's rotation and revolution constant?

Answers

The moon orbits the Earth once every 27.322 days. It also takes approximately 27 days for the moon to rotate once on its axis. As a result, the moon does not seem to be spinning but appears to observers from Earth to be keeping almost perfectly still. Scientists call this synchronous rotation.

How many molecules are there

Answers

Answer:

about 129-130

Explanation:

Which of the following do genes NOT do?
А
provide instructions for how a person grows
B
control how a person looks
C
decide whether or not a baby is born
D
get passed down from parents to children

Answers

Answer:

c.) decide whether or not a baby is born

Explanation:

I hope this helped you:)

In all of these organisms, which microscopic structures carry out major life functions?

Captionless Image
A) Chloroplasts
B) Cells
C) Wings
D) Antennea

Answers

U answer is option B Cells

Answer:

B) Cells

Explanation:

Cells are the basic unit of structure of Life. Without cells we wouldn't exist.

Bio homework help
pedigrees

had to reupload because of bots
NO ANSWERS THAT REQUIRE ME TO OPEN A FILE OF DOWNLOAD. NO FILES AT ALL!!!!!!!!!!!!!!!!

Answers

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The question is which ecosystem would be more likely to survive if a disease killed the grasses
Please help me I beg you

Answers

Answer:

I believe the answer is 3

Explanation:

Asap i need help pls​

Answers

Answer:

The right answer is C

Explanation:

Answer:

C

Explanation:

Because in ecosystem 1, the animals that eat insects have more sources of food than just insects, so that ecosystem would surive if the insects were to decline since the animals dont depend on JUST insects to surive

How is the Greenpeace organization monitoring the situation with ozone?

Answers

Answer:

By reducing the emission of CFC's gases.

Explanation:

The Greenpeace organization monitoring the situation with ozone by reducing the emission of CFC's gases that causes depletion of ozone layers. This organization reduces the use of fossil fuels and promoting renewable energy in order to prevent changes in the climate. The  Greenpeace organization ensures the use of those machines which can't produce CFCs and HFCs because one chlorine which is present in these gases destroys 100000 ozone molecules.

What is meant by nucleoid?​

Answers

Answer:

The nucleoid is an irregularly shaped region within the prokaryotic cell that contains all or most of the genetic material. 

What are the factors you see that contribute to the presence of spores in your chosen area?

Answers

Answer: The most important factors that contribute to the spore resistance properties are the low water content (25–60% of wet weight), elevated levels dipicolonic acid (DPA) (25% of core dry weight) chelated with calcium (Ca-DPA) and the saturation of DNA with α/β-type small acid soluble proteins (SASP) [69].

Explanation:

help!
look at photo to answer

Answers

The first one bro disnfhjdnfisbe

the fossil fules are used as energy sources but they cause pollution and are what​

Answers

Answer:

The correct answer is - non-renewable.

Explanation:

The non-renewable source of energy is the source of energy that can not be replaced naturally in the manner and the pace of the consumption of these sources. Nuclear, oil, fossil fuels, natural gases and other are an example of these type of energy source.

Fossil fuels were generated due to the decomposition of the dead plants and animals within the Earth over millions of years therefore these are called fossil fuels. These fuels are cause pollution by burning.

Chyangras are only farmed in cold regions. Give reasons.​

Answers

Answer:

hope this helps

Explanation:

Pashmina wool is a natural adaptation of the Chyangra goat that protects the animal from extreme weather conditions around the Himalayas. That is why they are farmed only in cold regions.

Who are Chyangra Goats?

Chyangra goat is a type of famous breed of mountain goats which is found in the high altitude areas of the Himalayan region. It produces the world's most expensive and finest quality of luxurious cashmere wool. It is also used for meat. They are more famous for the development of the world famous pashmina wool industry in Nepal and India.

Pashmina wool is a natural adaptation of the Chyangra goat that protects the animal from extreme weather conditions around the Himalayas. The specialty of pashmina is that it can retain enough heat to protect the animal from the severe cold and strong wind of the high mountains all year round.

Thus, Pashmina wool is a natural adaptation of the Chyangra goat that protects the animal from extreme weather conditions around the Himalayas. That is why they are farmed only in cold regions.

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Can someone explain to me about how the pereodic table is used

Answers

It’s the initials for the word

Answer:

So basically the rows are called periods, and the columns are called groups. The groups show that those elements have similar characteristics. There are also different families such as the noble gases and alkali earth metals. The elements are placed where they are because of the atomic number which is directly equal to the number of protons there are. The atomic mass is the number of both protons and neutrons. Also, even though the number of protons can be equal to the number of electrons, that isn't always the case. It could be an isotope which is basically for when an element or atom isn't neutral. Umm, so, I hope this helped. I know it's very long but if you need anything else just ask!! c:

PLEASE PLEASE HELP! No websites please!

Answers

Answer:

Igneous rock

:D

Can someone please help me answer this question? Thank you.

Answers

Answer:

The correct answer is -

C is parent cell

A is under meiosis

B is a sex cell

Explanation:

In the given question, the diagram shows three different cells in which the cell C is the parent cell that is about to undergo meiosis that can be identified by the quantity or numbers of chromosomes present in the cell which is highest among all.

The cell that is already in the meiosis is cell A, it is the cell that is produced after meiosis 1 in the meiosis cell division as it has half number of chromosomes to parent cells.

The sex cell or gamete is cell C that has a haploid number of chromosomes which makes this process reduction division

3. The air you breath in provides _____________________ for your cells

Answers

Answer:

Energy

Explanation:

Cells use the oxygen that you breathe in to provide energy for themselves.

Answer:

Energy

Explanation:

it's provides energy to enable the taking place of all living processes that occur in the cell

DOES ANYONE KNOW HOW TO SOLVE THIS??

Answers

Answer:

nope

Explanation:

only on here for points sorry

?????????????????????

Can a person with Rh-blood safely receive blood from either Rh+ or Rh-blood?

Answers

Answer:

Yes

Explanation:

Since the person already has Rh in their blood, it does not matter whether the donated blood is Rh+ or Rh-. getting Rh- blood for a Rh+ person is not harmful, unlike when it is vice versa.

Hope this helps :)

why won't ocean plants thrive in fresh water

Answers

Answer:

The salt doesn't flow into the cells much and the water doesn't leave much. Algae and plants can get away with having water attracted into their cells because they have a rigid cell wall outside the delicate cell membrane.

Answer:

the amount of salt in ocean water vs fresh water

Explanation:

Can anyone one helps me to fill in the 3 blanks with herbivore and carnivore and scavenger
Help!!

Answers

Answer: The kangaroo is a herbivore , the ants are scavengers and what I think is an ant eater is the carnivore.

Explanation:

A hurricane hits a coastal prairie and destroys the habitat. Years later, there is an appearance of small plants with rapidly spreading roots. This is an example of- *

Answers

Answer:

Secondary succession

Explanation:

Answer:

microhabitat

Explanation:

Years later there is an appearance of small plants with rapidly spreading roots on newly formed coastal sand dunes. This vegetation describes— A a microhabitat

Imagine that an area was set aside to relocate orangutans displaced from their rainforest habitats. A solution like this would involve many groups of people and careful considerations. Review the questions below, then develop at least two additional questions that could be considered.

What do orangutans use for shelter in their native ecosystem?
How much area does a specific number of orangutans need?

Answers

Answer:

a) Orangutan prefer to shelter in leafy trees or only leaves

b) One territory is of size 9 sq. km.

Explanation:

a) Orangutans spend a large part of their life in tropical rainforest trees. They prefer to sleep on the bunch of green trees and protect themselves from harmful weather conditions by using broad leaves of rainforest trees.

b) Each individual territory of a male Orangutan is near about 9 sq. km. and can extend up to 15 square kilometer. In one territory only one male lives along with other females and young ones.

What is the relationship between a chromosome and DNA?

Chromosomes manufacture DNA.


Chromosomes are made of DNA.


DNA is made of chromosomes.


DNA manufactures chromosomes.

Answers

Answer:

(B)  Chromosomes are made of DNA.

Explanation:

i took the test <3

Chromosomes are made of DNA which shows the relationship between a chromosome and DNA. So, the correct option is B.

What are Chromosomes?

A chromosome is indeed a lengthy DNA molecule that contains all or a portion of an organism's genetic code. The very long, thin DNA fibres in most chromosomes are covered with packing proteins; in eukaryotic cells, the histones are the most significant of these proteins.

Each cell's nucleus contains chromosomes, which are structures that resemble threads and contain the DNA molecule. Each chromosome is constructed from DNA that has been tightly wound around proteins called histones numerous times to support its structure. The fact that DNA is a component of chromosomes demonstrates the connection between chromosomes and DNA.

Therefore, the correct option is B.

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You are observing a woodland habitat and take note of a few trophic
relationships. You identify a few species of ferns that are being eaten by beetles.
You are also able to observe a snake in the process of eating a small species of
finch. You analyze your notes later and realize you missed a part of the food
chain. What part are you missing?
A. Tertiary Consumer eating Producer
OB. Secondary consumer eating Tertiary Consumer
C. Producer eating Primary Consumer
D. Secondary Consumer eating Primary Consumer

Answers

By analyzing the notes, one can say that in the given scenario, secondary consumer eating primary consumer is missing. The correct option is D.

What are consumers?

A consumer in a food chain is a living being that consumes organisms from another population. A heterotroph is a consumer, and an autotroph is a producer.

As in the notes it is mentioned that ferns are eating beetles, and snakes are eating finch. It is lacking secondary consumers eating primary consumers.

Thus, the correct option is D.

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. A scientist discovers a new object in the Kuiper Belt and claims it is a dwarf planet. What would have to be true about the object for the scientist to be correct?

Answers

Answer:

The object would have to be spherical, orbit the Sun, and be traveling in a path with other objects.

Explanation:

Just outside of Neptune's orbit is a ring of icy bodies. We call it the Kuiper Belt. This is where you'll find the dwarf planet, Pluto. It's the most famous of the objects floating in the Kuiper Belt, which are also called Kuiper Belt Objects, or KBOs.

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