A young man recently learned from a genetics doctor that he had a condition called Friedreich's ataxia. This syndrome affects the arms and the legs with the person usually needing a wheel chair. Neither of his parents have this disorder. However the young man's grandfather was wheelchair bound, but didn't know why because genetic information was very limited when his grandfather grew up. Based on this information, what type of inheritance does Friedreich's ataxia follow? Explain why. What are the genotypes of each of the individuals mentioned in this question? Create a pedigree chart to support your answer.​

Answers

Answer 1

Answer: Friedreich ataxia is a genetic condition that affects the nervous system and causes movement problems. People with this condition develop impaired muscle coordination (ataxia) that worsens over time. Other features of this condition include the gradual loss of strength and sensation in the arms and legs; muscle stiffness (spasticity); and impaired speech, hearing, and vision. Individuals with Friedreich ataxia often have a form of heart disease called hypertrophic cardiomyopathy, which enlarges and weakens the heart muscle and can be life-threatening. Some affected individuals develop diabetes or an abnormal curvature of the spine (scoliosis).

Most people with Friedreich ataxia begin to experience the signs and symptoms of the disorder between ages 5 and 15. Poor coordination and balance are often the first noticeable features. Affected individuals typically require the use of a wheelchair about 10 years after signs and symptoms appear.

About 25 percent of people with Friedreich ataxia have an atypical form in which signs and symptoms begin after age 25. Affected individuals who develop Friedreich ataxia between ages 26 and 39 are considered to have late-onset Friedreich ataxia (LOFA). When the signs and symptoms begin after age 40 the condition is called very late-onset Friedreich ataxia (VLOFA). LOFA and VLOFA usually progress more slowly than typical Friedreich ataxia.

Answer 2

The genotype of the grandfather and the young man is ff (f allele for  Friedreich's ataxia) The genotype of the father and the mother is Ff.

What is a genotype?

A genotype is a classification of the type of variant found at a certain position (i.e., a locus) in the genome. Symbols can be used to symbolize it.

Friedreich ataxia is a hereditary disorder that causes movement issues by affecting the neurological system. This disorder causes decreased muscular coordination (ataxia), which worsens over time.

Individuals with Friedreich ataxia frequently have hypertrophic cardiomyopathy, a type of cardiac disease that enlarges and weakens the heart muscle and can be fatal. Some people who are impacted have diabetes or an irregular spine curvature (scoliosis).

Therefore, the genotype of the grandfather and the young man is ff (f allele for Friedreich's ataxia) The genotype of the father and the mother is Ff.

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Related Questions

I WILL GOVE BRAINLIEST!!!

Male and female reproductive cells are collectively known as:

Spores

Gametes

Pollen

Offspring

Answers

Answer:

gametes is the answer so the male and female reproductive cells are collectively know as gametes

Answer:

b gametes

Explanation:

These sex cells are also called reproductive cells or gametes.

Where would you expect a maritime tropical air mass to originate?

Answers

Answer:

Maritime tropical air masses originate over the warm waters of the tropics and Gulf of Mexico, where heat and moisture are transferred to the overlying air from the waters below.

Explanation:

which of these provided information about animal adaptations to climate change?
a. fossils
b. ice cores
c. tree rings
d. sea-floor sediment

Answers

Answer: floor

Explanation:

Fossils are structures which provided information about animal adaptations

to climate change.

Fossils refers to remains of living organisms which have been replaced in the form of rock particles due to its presence in the soil for a long period of time.

The fossils contain an understanding of the structures and characteristics

the animals had which is then compared to its present structures. This helps

to explain how the animals adapted to climate change through changes in

the structure, shape of parts of the body.

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What role did the detergent play when added to the strawberry solution?

Answers

Answer:

when added the salt and detergent mixture to the smashed strawberries, the detergent helped lyse (pop open) the strawberry cells, releasing the DNA strands could gather and clump,making it easier for you to see them.

Which statement describes how maps represent Earth's surface? They have a three-dimensional surface. They use symbols to represent land features. They all use the same scale to show distance. They accurately represent the relative shape of Earth.

Answers

Answer:

B. They use symbols to represent land features.

Explanation:

In Geography, topography can be defined as the shape and structure of the Earth surface. Thus, a topographic map is used to graphically describe this features.

A topographic map can be defined as an accurate and detailed graphical (two-dimensional) description, representation or records of both natural and man-made (artificial) features on the surface of the Earth.

A topographic map uses contour lines to represent points of equal elevation above sea level such as mountains, hills, plains, valley etc.

The two-dimensional model of a topographic map graphically represents the height of a mount and the steepness of a slope through the use of contour lines.

Contours can be defined imaginary lines used for connecting locations that are having similar elevations on the Earth's surface. These contour lines are typically used for modeling the three-dimensional shape of the Earth surface in a topographic map.

Hence, the statement which best describes how maps represent Earth's surface is that, they use symbols to represent land features.

Answer:

B. They use symbols to represent land features.

Explanation:

pls help I AM ON A TIMERR PLEASE

Answers

Answer:

They will move inside the cell cos the concentration inside the cell is too low

Explanation:

hope it helps

Answer:

2nd option

Explanation:

Describe how an organism's genotypes codes for their phenotype. In your answer use the vocabulary terms: Phenotype, genotype, DNA, mRNA and protein. Please dont answer if you dont know it.

Answers

Answer:

The organism's genotype encodes their phenotype because the genotype corresponds to the characteristic that is determined by genes —formed by fragments of DNA— which are transcribed into mRNA to be translated into amino acid sequences in the synthesis of proteins, determining the morphological and functional characteristics of an organism, that is, its phenotype.

Explanation:

Genotype corresponds to the genetic information contained in the DNA, according to the sequence of nucleotides in its molecular structure. This genotype includes characteristics or polymorphisms that define the appearance and function of living beings.

Each DNA molecule constitutes a chromosome, formed by genes —DNA fragments— each of which determines specific characteristics.

When DNA is transcribed into mRNA, information is being sent that is necessary for the incorporation of amino acids into a protein that is being synthesized. The proteins, in turn, determine morphological and functional characteristics that constitute the phenotype of an individual.


What two components are often found as part of
an enzyme?

Answers

Answer:

The two components which are often found as part of an enzyme are Active site and protein. Proteins are referred to as macromolecules or macromolecules which consists of more or one of a chain of amino acid residue. They do perform an array of functions which are within organisms.

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Which of these best describes Earths crust? (
Inner layer consisting of two parts
Middle layer, density increases with depth
Top portion called asthenosphere, thickest layer
Thinnest under the oceans and thickest under continents

Answers

Answer:

Thinnest under the oceans and thickest under continents

Explanation:

Answer: Thinnest under the oceans and thickest under continents

It would be best to use a collecting net to catch which of the following insects?
A. Ground Beetles
B. Gnats
C. Ants
D. Grasshoppers

Answers

Answer:

d. grasshoppers

Explanation: ground beetles dont fly or anything like that. gnats are to small for a net. ants are also to small for that

what makes one mineral harder than the other? Explain

Answers

Answer:

The hardness of a mineral is mainly controlled by the strength of the bonding between the atoms and partly by the size of the atoms. It is a measure of the resistance of the mineral to scratching, the Mohs scale is for natural minerals.

Answer:The ones that are tightly bound together look different than do ones with looser bonds. For example, in the illustrations below, (A) shows the atomic structure of carbon in a diamond, and (B) is the carbon arrangement in graphite. (A) is more compact than (B), hence it is harder.

Explanation:Rocks are made of minerals, and different minerals have different crystal structures. The chemical bonds that hold atoms together in these minerals are stronger in some than in others, and the atoms themselves determine which bonds are stronger than others.

CAN SOMEONE HELP ME ON THIS BIOLOGY QUESTION OR LIKE GIVE THE LINK TO THE ANSWERS PLZ

Answers

I happen to just have done this but I only have the amino acid sequence and mRNA sequence hope it’s of some help here are the answers:

1. mRNA sequence: A U G A A C G C U G C C A G U A U G
Amino acid sequence: methionine asparagine alanine alanine serine methionine

2. mRNA sequence: AUG AAC CCU GCC AGU AUG
Amino acid sequence: methionine asparagine proline alanine serine methionine

3. mRNA sequence: AUG AAC GCC UGC CAG UAU G
Amino acid sequence: methionine aspargine alanine cysteine glutamine tyrosine then I believe a stop codon for G


Studying____
we infer how Pangea split into continents

Answers

Answer:

Scientists believe that Pangea broke apart for the same reason that the plates are moving today. The movement is caused by the convection currents that roll over in the upper zone of the mantle.

Explanation:

Answer: Pangea broke apart for the same reason that the plates are moving today. The movement is caused by the convection currents that roll over in the upper zone of the mantle.

Explanation: Scientists believe that Pangea broke apart for the same reason that the plates are moving today. The movement is caused by the convection currents that roll over in the upper zone of the mantle. About 200 million years ago Pangaea broke into two new continents Laurasia and Gondwanaland.

Select all that apply.
Which of the following statements are true?
A purebred organism can either be TT or tt.
The combination of two genes determines the genetic trait of an organism.
Recessive genes will sometimes be masked by dominant genes.
It is possible for two genetically different plants to have the same phenotype.

Answers

Answer:

A purebred organism can either be TT or tt.

It is possible for two genetically different plants to have the same phenotype.

Explanation:

What is the temperature of Jupiters surface?

Answers

Answer:

minus 234 degrees Fahrenheit  or minus 145 degrees Celsius

Explanation:

present and debate current social and ethical implications of biotechnology and genetic engineering

Answers

Answer:

These concerns range from ethical issues to lack of knowledge on the effects genetic engineering may have. One major concern is that once an altered gene is placed in an organism, the process cannot be reversed. Public reaction to the use of rDNA in genetic engineering has been mixed.

I don't know if that's right

When a continent is closer to the equator the climate is

Answers

The climate is Tropical.
Hope this helps :)

Answer:

The closer a continent is to the equator, the warmer it will be.

Explanation:

The middle of the earth is its largest point, and is therefore closer to the sun than any other area. It is also in more direct sunlight, and has warmer climates.

How might volcanic eruptions change the flow of energy on earth?

Answers

Answer:

It causes global warming due to emission of carbondioxide gas.

Explanation:

Volcanic eruptions change the flow of energy on earth by emitting gases such as carbondioxide and sulfur dioxide gases. Volcanic gases like sulfur dioxide is responsible for global cooling by reflecting solar radiation back to the space, while on the other hand, carbon dioxide emitted from volcanoes, has the ability to promote global warming by blocking solar radiation. If the amount of carbondioxide gas is higher as compared to sulfur dioxide gas so global warming occurs.

A person with cystic fibrosis would have which genotype?

Answers

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene which encodes a protein expressed in the apical membrane of exocrine epithelial cells.

How does the structure of the
different seeds allow them to move and to grow into a new plant?

Please help it’s due today!

Answers

Answer:

Because plants cannot walk around and take their seeds to other places, they have developed other methods to disperse (move) their seeds. The most common methods are wind, water, animals, explosion and fire. Dandelion seeds float away in the wind.

Explanation:

describe the subcellular structures that found in all bacteria​

Answers

Answer:

The subcellular structures found in bacteria are: cell wall, cytoplasmic membrane, cytoplasm, ribosomes, vacuoles, plasmids, nucleoid —circular DNA— and annexes, such as pili, cilia and flagella.

Explanation:

Bacteria are unicellular prokaryotic organisms, characterized by a simple structure, lacking a nucleus and most of the organelles, with a circular DNA molecule that is free in the cytoplasm.

The sub-cellular structures present in the bacetry are

Cell wall, surrounding the plasma membrane, composed of peptidoglycan. Plasma membrane of lipidic nature, which covers and protects the cytoplasm.  It is possible to find in some bacteria two plasma membranes.Cytoplasm, lacking endomebrane system. Nucleoid is not a true nucleus with nuclear membrane, but corresponds to circular DNA that is free in cytoplasm. Plasmids are fragments of DNA that are associated with the nucleoid, useful for the exchange of genetic material with other bacteria. Ribosome, which participate in the synthesis of bacterial proteins.Vacuoles are structures that are responsible for the storage of reserve substances, useful for bacterial metabolism. The structures annexes to bacteria are the pili, cilia and flagella. The pili are small villi present on the bacterial surface and participate in the process of intercellular communication and conjugation in prokaryotes. Cilia and bacteria serve for the mobility of bacteria.

Should the thruster fire exert force in the same direction or opposite direction to bring the Pod to a stop? Explain.

Answers

Answer: Explain the claim : Firing the thrusters would have caused the pod to move in the opposite direction. The pod would have had to have a lighter mass meaning a smaller amount of force would have had to be exerted onto the pod making it move in the opposite direction.

Explanation:

What foods from each food group would provide a balanced breakfast


HSLSODIDBDLDO HELP

Answers

Answer:

A well-balanced breakfast includes foods from at least three out of the five food groups. Whole grain breads and cereals; low-fat dairy products, and fruit are typical breakfast choices. Choosing a high-fiber cereal with low-fat milk or yogurt for breakfast has been linked to improved weight or weight loss.

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Answer:

Whole grains, low-fat dairy products, fruit, lean protein

Explanation:

Whole Grain- Cereal, toast, whole grain waffles

Dairy Products- Milk, yogurt

Fruit- Apple, grapes, oranges, etc.

Lean Proteins- Eggs or nuts

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Directions Part TWO: Create a short story about your life as a droplet of water. Water can exist in many locations at any point in time. Pick any location or step of the water cycle to begin your journey. Your starting point could be a cloud, ocean, river, deep ground water etc. Choose a starting location and then fully explain with detail how you will travel throughout the entire water cycle. Be sure to include any changes in your heat energy along the way. You must include the following terms Evaporation, Condensation, Precipitation, Run-off, Collection, Deep groundwater, Increased heat energy, Decreased Heat Energy, Gas, and Liquid) Goodluck!!!


Its a simple assignment but i dont know what to say pls help me​

Answers

Answer:

It is very simple...

Explanation:

just answer it with your own thoughts of life....

Answer: Just look up water cycle images on the internet. You can also make it look like the water droplet is going through some hardships along the way.

Discuss the bone under the following headlines: Composition, type, parts and structure.​

Answers

Answer:

Explanation:

hgd

Answer:

Bones are composed of two types of tissue:

1. Compact (cortical) bone: A hard outer layer that is dense, strong, and durable. It makes up around 80 percent of adult bone mass.

2. Cancellous (trabecular or spongy) bone: This consists of a network of trabeculae or rod-like structures. It is lighter, less dense, and more flexible than compact bone.

Also found in bones:

osteoblasts and osteocytes, responsible for creating bone

osteoclasts or bone resorbing cells

osteoid, a mix of collagen and other proteins

inorganic mineral salts within the matrix

nerves and blood vessels

bone marrow

cartilage

membranes, including the endosteum and periosteum

Explanation:

What is an Igneous Rock?

rock that forms when existing rock changes to a new rock because of heat and pressure


rock that forms by the process of compaction and cementation of sediments


rock that forms when melted rock (magma, lava) cools and hardens

Answers

Answer:

rock that forms when melted rock (magma, lava) cools and hardens

Explanation:

Igneous rock, or magmatic rock, is one of the three main rock types, the others being sedimentary and metamorphic. Igneous rock is formed through the cooling and solidification of magma or lava. The magma can be derived from partial melts of existing rocks in either a planet's mantle or crust.

Brainliest plz

1) In pea plants, purple flowers are dominant to white flowers. If two white flowered plants are crossed,
what percentage of the plants will be purple?
Explain your reasoning using a punnett square and a short written explanation.

Answers

Answer:

all white

If students are stuck on this one, advise them to make a "key" to help them sort it out.

PP = purple, Pp = purple, pp = white

Explanation:

4. Thermal conduction works when two objects are in_______with each other. The_________
energy of the molecules causes them to bounce into each other, causing heat to move through
the object.

Answers

The first line is motion

Scientists are looking to determine the primary productivity of a lake by analyzing its oxygen net primary productivity. How are scientists able to measure how much oxygen is used during a plant’s cellular respiration processes?(1 point)

by observing cellular respiration under bright light conditions

by observing cellular respiration only when photosynthesis occurs

by observing cellular respiration by studying biomagnification

by observing cellular respiration under the absence of light

Answers

Question: "Scientists are looking to determine the primary productivity of a lake by analyzing its oxygen net primary productivity. How are scientists able to measure how much oxygen is used during a plant’s cellular respiration processes?"

Answer: "Out of all the options given, the best way for scientists to have the chance to measure the usage of oxygen during a plant's cellular respiration processes would be by 'observing cellular respiration under the absence of light'. So, I would say the best option would be Option D. "

To measure how much oxygen is used during a plant’s cellular respiration processes, scientists did by observing cellular respiration in the absence of light, hence option D is correct.

How to measure oxygen level?

As a result, in the absence of photosynthesis, there would be no glucose or oxygen for respiration, and since photosynthesis requires carbon dioxide, only anaerobic respiration would be possible.

Examining a lake's oxygen net primary production, researchers hope to ascertain the lake's primary productivity. By monitoring the output of oxygen or the intake of carbon dioxide, primary productivity is typically calculated. The standard unit of measurement for production rates is grams of organic carbon per unit area per unit of time.

Therefore, observing cellular respiration in the absence of light.

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Which of the following is true about moss sporophytes?
a. Sporophytes perform photosynthesis. C. Sporophyttes contain a single spore.
b. Sporophytes depend on the gametophyte for d. Sporophytes are very large.
nutrients.

Answers

Answer: sporophytes photosynthesise, particularly when immature, but depend on gametophytes for at least 50% of nutrient requirements

Explanation: In mosses, the gametophyte generation is the dominant generation unlike in higher plants. The diploid sporophyte generation produces several spores per capsule.

Answer:

c

Explanation:

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