Again, imagine that your liver, which has a volume of 2 liters, developed from a single embryonic precursor cell with a volume of 1000 μm3, or 1 x 10-12 liters. You previously calculated how many cell division cycles would be required for the precursor cell to produce your mature liver.

What if the control of liver organogenesis were a bit faulty, and the process went exactly 2 cell division cycles beyond this? What then would be the volume of your liver in liters?

I found that the answer to the first question is 41, but I can't figure out the second part.

Answers

Answer 1

Answer:

41 cycles

If cell division went 2 cell division cycle beyond the  precursor; we have 43 cycles

The volume would be = 17.59 Litres

Explanation:

From the given information:

The number of cells in the liver that developed from an embryonic precursor is roughly [tex]\dfrac{2}{10^{-12}}= 2\times10^{12}[/tex]

The number of cell cycles needed to produce [tex]2\times 10^{12[/tex]  cells is:

= [tex]log_2(2\times 10^{12})[/tex]

= 40.86

[tex]\simeq[/tex] 41

Thus, nearly 41 cycles of cell division are required to form the mature liver.

Now;

Suppose 2 extra cell division cycles took place;

The total number of cells would be 2⁴³ = 1.759 × 10¹³; &

The volume would be =  1.759 × 10¹³ × 10⁻¹²

The volume would be = 17.59 Litres


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Prokaryotic Chromosome

Prokaryotic cells typically have a single, circular chromosome located in the nucleoid.

Download DNA Lab Activities

2. Each chromosome contains a molecule of DNA that is supercoiled and compacted by nucleoid-associated proteins (NAPs).

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Here’s how the characteristics of eukaryotic and prokaryotic chromosomes compare.

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Shape Linear Circular

Size Large Small

Number Multiple Single

Location Nucleus Nucleoid (region in cytoplasm)

Storage proteins Histones Nucleoid-associated proteins

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 External Sources

“The Precarious Prokaryotic Chromosome” from the Journal of Bacteriology.

A video on DNA topology and supercoiling from the MITx Molecular Biology course.

“Nucleoid Associated Proteins: The Small Organizers That Help to Cope With Stress” from Frontiers in Microbiology.

An article from Scitable/Nature Education on genome packaging in prokaryotes.

An article from Khan Academy about binary fission in bacteria.

“The Vibrio cholerae genome contains two unique circular chromosomes,” from the Proceedings of the National Academy of Sciences.

Definitions of plasmids from Scitable and the National Human Genome Research Institute.

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