Which of the following studies is linked most directly to the establishment of the National Research Act in 1974 and ultimately to the Belmont Report and federal regulations for human subject protection ?
A. The Public Health Service Tuskegee Study of Untreated Syphilis in the Negro Male.
B. Stanford Prison Experiment (Zimbardo)

Answers

Answer 1

The 40-year Tuskegee syphilis study led to passage of the National Research Act of 1974. It is called most notorious biomedical study in U.S. history and leading to Belmont Report (1979), establishing OHRP (Human Research Protections), federal laws and regulations.

What are the lasting consequences of the National Research Act 1974?

The National Research Act was enacted by the 93rd Congress of the United States and signed into law by President Richard Nixon on July 12, 1974. The National Research Act of 1974 established the National Commission for the Protection of Biomedical and Behavioral Research Subjects. Definitions of guidelines, ethical principles and rules were the result of deliberations of national committees.

Which of the following three principles are included in the Belmont Report?

Three fundamental principles universally recognized in our cultural tradition are particularly relevant to the ethics of research involving humans principles of individual respect, beneficence and justice.

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Related Questions

A nurse is discussing the norming stage of the group development process with a student nurse. Which of the following statements by the student indicates an understanding of the discussion?
-"This stage involves constructive efforts on the part of the group members."
-"This stage is when testing occurs to identify boundaries of interpersonal behaviors."
-"Consensus evolves in this stage."
-"Resistance is evident as subgroups for in this stage."

Answers

"Consensus occurs in this stage." statement by the student which indicates an understanding of the discussion.

Each stage of group formation marks a distinct and crucial point in the team growth process. As the group moves down the list, it strengthens its aims, broadens the competencies of its team members, and enables the group members to work more successfully toward their final goal. The rest of this course will go over each individual stage of group growth and how it affects the building of the a healthy, cohesive group.

Bruce Tuckman, a psychologist, devised his group development model in 1965 that describe how healthy teams cohere over time. Tuckman's approach posits five stages of group development: forming, storming, norming, performing, then adjourning.

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How will participation in physical activities help you improve your physical aspect?

Answers

better blood flow, stronger muscles, stronger lungs, and better state of mind

In cases of sexual assault, it is important to ensure that you do which of the following? - Immediately write down your observations of the scene before assessing the patient. - Call for a female EMT or ALS care provider. - Discuss with law enforcement any suspicions that you may have about the perpetrator. - All of these answers are correct.

Answers

The answer is all of the answers are correct but first attend to the patient before anything else.

What are three things you could do if you were asked to become an advocate?

Answers

Give individuals healthy living lessons and educate them on health and wellbeing by pursuing a career as a health coach.

There are several things one may do since becoming a health and wellness advocate, three of which are described below.

One of the most visible things one may do is work in preschools to teach children about wellness, or teach community groups, or participate in conferences and collaborations linked to health initiatives.

It is possible to give crucial health care to impoverished individuals while also fostering dialogue between clinics & community members.

By pursuing a career as a health coach, one may teach others about healthy living and educate them about wellness and health. Counsel persons who need help finding a healthy lifestyle & wellness coach.

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A conscious memory of the name of the first president of the United States is a(n) ______ memory
a. explicit
b. procedural
c. iconic
d. nondeclarative

Answers

A conscious memory of the name of first president of U.S. is an explicit memory. Explicit memory involves facts and experiences that a person can consciously know and claim.

How is explicit memory different from implicit memory?

There are two types of long-term memory. In addition to implicit memory, there is also explicit or declarative memory. Explicit memory involves remembering events and facts. Unlike latent (implicit) memory that you use unconsciously, it takes conscious effort to retrieve things from your explicit memory.

Where are explicit memories stored?

Explicit memories are related to events that happened to you (episode), as well as facts and general information (semantics) – there are three important areas of the brain: hippocampus, neocortex, and amygdala. Latent memories, such as motor memories, are based on the basal ganglia and the cerebellum.

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What are the side effects of heat exhaustion?

Answers

Heat exhaustion has the following side effects:

Sweating profuselySkin that is cold, pallid, and clammyA quick, feeble pulseVomiting or nauseaCramping of the musclesFatigue or weaknessDizziness

Heat exhaustion occurs when the body overheats (heats up) and is unable to cool itself down. During exercise or other physical activity, your body might overheat, particularly in hot, humid conditions.

Sweating is how the body loses fluids while you exercise. You can get dehydrated if you do not replenish those fluids with water or other drinks. Heat exhaustion can also be caused by dehydration.

Heat exhaustion symptoms consist of dizziness, headache, nausea, muscular cramps, and others. Removal from of the heat, rest, and fluids are all part of the treatment. Heat exhaustion, if left untreated, can progress to heatstroke, a potentially fatal illness.

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Is the food pyramid still used?

Answers

Answer:

Yes, it is still in use.

Explanation:

The classic food pyramid was replaced in 2005 by a funky pyramid with a figure climbing upstairs on the side. If you don't remember this, don't worry — it wasn't around long. In 2011, the new food pyramid was replaced by the USDA's MyPlate. It is still in use. Hope you understand.

What characteristics of the face and body show good health?What characteristics show bad health?

Answers

Answer:Drooping eyelids

Explanation:

Doctors call it ptosis or blepharoptosis. It can happen in one or both eyes -- in severe cases, your eyelid may block your vision. You may be born with it or get it over decades. It’s often harmless, but it can be a sign of problems with your brain, nerves, or eye socket. See your doctor if it happens in days or hours, or if you have double vision, weak muscles, trouble swallowing, or a bad headache -- those can be signs of a stroke.

How to manufacture a benefit by using fewer scarce resources?

Answers

Societies can combat scarcity by expanding their supply. There will be less scarcity the more commodities and services that are accessible to everyone. Of course, expanding supply is constrained by factors like manufacturing capacity, usable land, time, and the like.

What are the four scarce resources?

Natural resources are inherently scarce, including gold, oil, silver, and other fossil fuels. These resources grow scarce and their prices may rise as demand outpaces supply. Due to their scarcity and market dominance, some commodities, like diamonds, attract a premium price.

Why are limited resources crucial?

Understanding scarcity will help you better grasp how commodities and services are priced. Gold, diamonds, and specific types of knowledge are examples of things that are valued because they are hard to come by and can command greater prices from vendors.

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What are the 4 key recommendations for a healthy lifestyle?

Answers

The four key recommendations for a healthy lifestyle are eating a balanced and nutritious diet, regular physical activity, avoiding smoking and limiting alcohol consumption, and getting enough good quality sleep.

The four key recommendations for a healthy lifestyle are:

Eating a balanced and nutritious diet: This includes consuming various fruits, vegetables, whole grains, lean proteins, and healthy fats.Regular physical activity: Regular physical activity can improve cardiovascular health, strengthen muscles and bones, and improve mental health.Avoiding smoking and limiting alcohol consumption: These habits can significantly reduce the risk of many chronic diseases.Getting enough good quality sleep: Aiming for 7-9 hours of good quality sleep can help improve physical and mental well-being.

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Why are lifestyle diseases increasing?

Answers

Lack of physical exercise, improper eating, alcohol, drug use disorders, and cigarette use all contribute to lifestyle illnesses, which can lead to heart disease, stroke, obesity, type II diabetes, and lung cancer.

Lifestyle illnesses are defined as diseases whose incidence is mostly dependent on people's everyday routines and is the outcome of an unsuitable interaction between individuals and their environment. Atherosclerosis, heart disease, and stroke are examples of lifestyle illnesses, as are obesity and type 2 diabetes, as well as smoking, drinking, and drug addiction issues.

Lifestyle diseases are illnesses caused mostly by people's everyday habits. Habits that prevent people from being physically active and push them toward sedentary lifestyles can lead to a number of health issues, including chronic noncommunicable diseases with potentially lethal consequences.

Diet and lifestyle choices are considered to play a significant role in illness risk. Substance use disorders, such as cigarette smoking and excessive alcohol use, as well as a lack of or excessive exercise, may raise the chance of acquiring certain diseases, particularly later in life.

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What are measurable objectives and why is it important that they be measurable?

Answers

Answer:here;

Explanation:

Measurable objectives are specific statements expressing the desired qualities of key services; and the expected results of the services/experience. Objectives should state: • Who is involved: The people whose behaviors, knowledge and/or skills are to be changed as a result of the program.

Which of the following would be considered part of a healthcare worker's role in the event of an emergency involving a biologic or chemical exposure ?
a. Recognizing an illness or injury as potentially resulting from exposure to a biologic, chemical, or radiologic agent
b. Instituting appropriate steps to limit the spread of an infection
c. Reporting identified cases or events to the public health system
d. All of the above

Answers

The following would be considered part of a healthcare worker's role in event of an emergency involving a biologic or chemical exposure : d.) All of the above.

What is a healthcare worker's role in the event of an emergency involving a biologic or chemical exposure ?

Potential biologic exposures include needle sticks, animal bites, aerosol exposures, and other incidents resulting in disease from a biological agent. Chemical exposure occurs when people have contact with chemical, directly or through another substance contaminated with the chemical.

Healthcare worker's role is recognizing an illness or injury as resulting from exposure to a biologic, chemical, or radiologic agent and  taking appropriate steps to limit the spread of an infection.

It is necessary to report identified cases or events to the public health system immediately.

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Mike is a 22 y/o male who comes to your clinic with a 5-day history of cough without sputum production. He states that his cough is worse in the morning and he has some hoarseness, post-nasal drip, and a low-grade fever. Mike has otherwise been healthy. Differentials for Mike might include which of the following

Answers

The cough reflex begins with irritant receptors in the vagus nerve being stimulated by afferents (cranial nerve X).

What are the five primary parts of the reflex arc?

A particular receptor, an afferent nerve fibre, an association neuron, an efferent motor neuron, and an effector organ comprise the reflex arc.

Encourage every two hours ambulation/repositioning. Pillows can be used to raise the head of the bed. To relieve sore throat, gargle or consume warm beverages. While awake, use PO Pepermints/cough drops.

When patients are unable to cough up secretions adequately owing to weakness, thick mucus plugs, or extensive or tenacious mucus production, suctioning is required.

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How can we positively affect the environment?

Answers

Going Green has a good impact on the environment.

Green living encourages individuals to live in a more ecologically responsible manner, and there are several methods to "go green." While most people realize that becoming green is beneficial for the environment, they may not completely comprehend the magnitude of its impact. Going green provides various environmental benefits, including cleaner water and air, the preservation of natural resources, and a reduction in the global warming impact.

Greenhouse gas emissions, such as carbon dioxide, are considered to have a substantial role in global warming. For example, the United States Department of Energy calculates that automobiles emit around 1.7 billion tones of carbon dioxide (CO2) every year. You may help to reduce their contribution to the warming problem by minimizing the length of time you travel, maintaining your vehicle, or driving a green automobile, such as a hybrid.

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A 42 year old male work out for 30 minute on the tationary bike, and ha a HR of 158 a oon a he finihe. One minute later, hi HR i 114, and 2 minute after he topped biking hi HR i 95. What i hi HRR (Heart Rate Recovery)?

Answers

Your age is subtracted from 220. A 30-year-maximal old's heart rate, for instance, is 220-30 = 190. Then, 114 to 152 (60% to 80% of 190) would be his desired heart rate range for cardio-respiratory activity.

What heart rate is ideal for my age?

Based on your age, you may calculate your maximum heart rate. Subtract your age from 220 to get a ballpark idea of your maximal age-related heart rate. For instance, the predicted maximum age-related heart rate for a 50-year-old person would be computed as 220 - 50 years = 170 beats per minute (bpm)

What is a heart rate that is unsafe?

The body's cardiac problems are reflected in abnormal heart rates or heart beats. This can occasionally be lethal if discovered and if untreated. Conditions where the heartbeat exceeds 120–140 beats per minute or drops below 60 beats per minute can be regarded as hazardous, necessitating urgent medical attention.

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Treating all human blood and OPIM a if it i known to be infected with a bloodborne dieae i known a

Answers

An approach to infection control is characterized as using universal precautions. All human blood and some bodily fluids are handled as if they were known to be contaminated with HIV, HBV, and other bloodborne viruses under the theory of universal precautions.

What exactly are Opim bloodborne pathogens?

Human blood contains dangerous germs known as bloodborne pathogens (BBP); along with other potentially infectious materials (OPIM), they can spread illness. Hepatitis B (HBV), hepatitis C (HCV), and the human immunodeficiency virus are among examples (HIV).

What three categories of bloodborne pathogens are there?

Three of the most prevalent bloodborne pathogens from which healthcare workers are at risk are the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV).

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Which benefit of stretching can make your mood better after exercise decreased joint stiffness improved ability to relax improved circulation improved posture

Answers

Pose variations that stretch and open up your body could aid in your daily relaxation. Both the physical and mental affects can be soothing.

What is meant by relaxation?

The negative impacts of stress on one's body and brain are lessened by this technique. You can control your daily stress by engaging in relaxation exercises. Additionally, these techniques can assist with persistent stress or stress linked to various medical conditions, such as heart disease and pain.

Which three relaxation techniques are there?

Breathe deeply and deliberately. Using a body scan, mental imagery, mindfulness meditation,  tai chi, and gong, as well as repetitive prayer, are all part of this simple yet powerful technique. You should also take very long, calm, deep breaths.

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The public health nurse is discussing immunizations with a group of caregivers of infants. One of the mothers asks the nurse why the child will need immunizations. Which of the following statements would be the most appropriate statement for the nurse to make to this mother?
a) "The immunities that the infant is born with are not for the same diseases they will be immunized against."
b) "The antibodies the fetus gets from the mother are in the placenta, so after birth they are no longer available to the infant."
c) "Infants are unable to develop antibodies to protect them from diseases so they must be immunized."
d) "The infant is born with immunity to some diseases, but those immunities decrease over the first year of life."

Answers

The best thing a nurse could say to this mother is that the infant is not born with the same immunity against the same diseases he is vaccinated (immunized) against.

What does immunization mean and why is it important?

The process of protecting a person from disease by vaccination. The term is often used interchangeably with vaccination or immunization.

Immunization saves lives. It protects you, your family, and your community. Immunization protects future generations by eradicating infectious diseases. Many infectious diseases are now rare or have been eradicated by immunization programs, but new infectious diseases are emerging around the world.

What is an example of immunization?

For immunization the recommended vaccines according to disease include:  Chickenpox (Varicella) Dengue. HPV (Human Papillomavirus)  Flu (Influenza). Diphtheria. Hepatitis A. Hepatitis B. Hib (Haemophilus influenzae type b)

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How is contemporary person-centered therapy different than it was in Rogers's day?

Answers

Contemporary Client-centered therapy is different because rather of just reflecting back their clients' remarks, therapists are more likely to encourage them towards discoveries.

Client-centered therapy differs from other forms of therapy in two ways. It Focuses on each client's uniqueness and avoids the therapist giving direction to the issues discussed.

Person-centered therapy is based on the belief that clients are resourceful individuals who can take responsibility for their own lives and solve their own problems. It emphasizes respect and respect for client autonomy and choice, and the client's role as an active participant in all aspects of therapy.

Rather than analyzing the client's difficulties in detail or blaming past experiences for the client's current thoughts and We provide an environment in which you can make informed decisions.

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Which of the following activities would a person most likely be performing when displaying this EEG pattern?
A. doing some light reading on a Saturday afternoon
B. napping at a hotel resort in the early evening
C. performing yoga in the middle of a garden
D. preparing a presentation for an important executive

Answers

For the given EEG pattern, the person is most likely to get engaged in preparing a presentation for an important executive, which means option D is the right answer.

EEG refers to Electroencephalogram, which shows the electrical signals obtained from the electrodes attached at the brain. Since the image shows that the intensity of electrical signals is high and their frequency (repetition of waves) is also high, this means that the person is involved in some important work which requires the use of brain in regular and continuous manner. During EEG test, some electrodes are inserted into the scalp of the head and then samples are taken for a particular stimulus given to the brain and the electrical activity is recorded in the electroencephalograph, which is the name of the device used. It helps in analysis of brain activity and any diseases related to brain.

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What i the role of health inurance portability and accountability act in the United State healthcare

Answers

A federal legislation known as the Health Insurance Portability and Accountability Act of 1996 (HIPAA) mandated the development of national standards to prevent the disclosure of sensitive patient health information without the patient's knowledge or consent.

The 104th United States Congress passed the Health Insurance Portability and Accountability Act of 1996, which President Bill Clinton then signed into law on August 21, 1996.

It addressed several constraints on healthcare insurance coverage, updated the flow of healthcare information, and outlined how personally identifiable information kept by the healthcare and healthcare insurance businesses should be safeguarded against fraud and theft.

It typically forbids healthcare organizations, also known as covered entities, from voluntarily releasing protected information to anybody but a patient and the patient's authorized representatives.

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Who is responsible for the Healthy Eating Pyramid?

Answers

Answer: The USDA

Explanation:

The Food Guide Pyramid was a recognizable nutrition tool that was introduced by the USDA in 1992.

What are four lifestyle choices which you could change to improve your overall health?

Answers

Four lifestyle choices that can be changed to improve overall health include eating a healthy diet, increasing physical activity, quitting smoking or limiting alcohol consumption, and improving sleep habits.

Four lifestyle choices that can be changed to improve overall health include:

Eating a healthy diet: Adopting a diet that includes a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats.Increasing physical activity: Incorporating regular exercise such as walking, cycling, or going to the gym into your daily routine.Quitting smoking or limiting alcohol consumption: Reducing or eliminating these habits can significantly reduce the risk of chronic diseases.Improving sleep habits: Aiming for 7-9 hours of good quality sleep every night and maintaining a consistent sleep schedule.It's important to note that these lifestyle choices are interrelated and have a cumulative impact on one's health. Making a positive change in one area can have a positive impact on other areas as well.

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Is there any reason why you do not engage in physical activity?

Answers

No, there is no such valid or logical reason for me not being able to engage myself in physical activity, it is just the laziness that prevents me from doing so.

Physical activity refers to any action or exercise or even sports which tend to use muscular energy in some form and the movement of core muscles and bones due to which the body feels tired and sweats. Physical activity tends to grow the activeness and physical fitness of the body. People refrain from participating in physical activity because they feel tired or exhausted of the daily chores and nowadays they get involved in digital or social media rather than physical workout. This takes them away from working physically to gain fitness of body, mind and soul.

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Can hormones turn genes on and off?

Answers

Yes, hormones can turn genes on and off. Transcription factors perform on signals from hormones, the terrain, and other cells perform to switch genes on or off.

Indeed in a specialized liver cell, some genes can subsist switched off when the protein they decode for isn't demanded.

frequently binding to receptors in the prey cell nucleus companies with the genes. In fact, in numerous cases, one hormone is done by spinning on the gene for another hormone, similar to thyroid-stimulating hormone triggering the gene that leads to the emulsion of thyroid hormone.

Hormones that Affect Gene exertion. Lipid-solvable hormones act generally by gene activation/ deactivation. exemplifications of these hormones involve steroids, thyroid hormones, and vitamin A( retinoic acid). The hormones are shipped through the rotation in connection with a hormone-chaining protein and are solvable in the plasma membrane of the cell.

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What is the right to liberty and life meaning?

Answers

Right to liberty and life focuses on protecting individuals' freedom from unreasonable detention, as opposed to protecting personal safety. One has a right to personal freedom, implies that you must not be imprisoned or detained without good reason.

What is the meaning of right to liberty and life?

The right to life is the belief that a person has the right to live and should not be killed by another entity.

As in the Constitution, liberty means freedom from arbitrary and unreasonable restraint on an individual. Freedom from restraint refers to not just physical restraint, but also the freedom to act according to one's own will.

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What is the 10 good lifestyle?

Answers

Ten good lifestyles are : healthy balanced diet, drinking lots of water, exercising regularly, plenty of sleep, not smoking, reducing alcohol consumption, keeping a check on mental and physical health, eat plenty of vegetables and some fruits every day, time management and do not skip breakfast.

What is a good lifestyle?

A good lifestyle refers to a positive attitude and means focusing on the good aspects of life and not worrying about the negative things in life. To attain a positive lifestyle, one must improve his/her approach towards life and the people they meet.

It is important to choose a diet that's low in saturated fat and cholesterol, and moderate in sugar, salt and fat.

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WHO has defined health as a state of complete physical mental and well-being and not merely an absence of disease?

Answers

Mental health is indeed a crucial and necessary component of overall health.

According to the WHO constitution, "health is a full condition of physical, mental, and social well-being, not only the absence of sickness or disability." This concept implies as mental health encompasses more than the absence of psychological diseases or impairments.

Mental health is a condition of well-being in which an individual recognizes his or her own potential, is able to cope with everyday stressors, can work efficiently, and can contribute to his or her community.

Our collective and individual ability as humans to think, emote, communicate with one another, make a job, and enjoy life is dependent on our mental health. On this premise, mental health promotion, protection, and restoration can be viewed as a critical issue of people, communities, and societies all over the world.

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What are some lifestyle changes?

Answers

Examples of lifestyle changes are eating a healthy diet, increasing physical activity, quitting smoking or limiting alcohol consumption, improving sleep habits, managing stress, improving hygiene, regular medical check-ups and screenings, building and maintaining positive relationships, continual learning, and self-improvement, and giving back to the community.

Some examples of lifestyle changes that can improve overall health and well-being include:

Eating a healthy diet: Adopting a diet that includes a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats.Increasing physical activity: Incorporating regular exercise such as walking, cycling, or going to the gym into your daily routine.Quitting smoking or limiting alcohol consumption: Reducing or eliminating these habits can significantly reduce the risk of chronic diseases.Improving sleep habits: Aiming for 7-9 hours of good quality sleep every night and maintaining a consistent sleep schedule.Managing stress: Finding healthy ways to manage stress, such as meditation, yoga, or exercise.Improving hygiene: Regularly washing hands, brushing teeth, and taking showers.Regular medical check-ups and screenings: Keeping track of your health by visiting the doctor and getting regular screenings.Building and maintaining positive relationships: Cultivating a support network of friends and family.Continual learning and self-improvement: Continually learning new skills and knowledge can improve mental stimulation and employability.Giving back to the community: Volunteering or participating in community service can have a positive impact on physical and mental well-being and can also have a positive impact on the community.

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Carol files a suit against Duffy in a state trial court and loses. Carola. can plead her case before a small claims court.b. cannot take her case any higher in the court system.c. can insist that the United States Supreme Court hear her case.d. can plead her case before an appellate court. You're fitting a pipe into an existing fitting. The fitting allows a diameter variance of 0.001". If the interior diameter of the pipe is 0.49" and the pipe thickness is 0.005", What's the maximum allowable pipe diameter? a. 0.496, b.0.501, c. 0.499, d. 0.541 Unit 5: Systems of Equations & InequalitiesHomework 3: Solving Systems by Elimination (Day 1) What is the difference between the weight of an object and the mass of an object? An object has 100 J of kinetic energy. If the objects mass doubles, what is its kinetic energy? hiwot is making coffee.change into passive voice What is the value of x in this triangle? What is the value of each angle? An object that is moving in uniform circular motion will definitely have a large acceleration if it is If the length of the American flag is 1.8 yards, find the hight Write three ratios that are equivalent to 75% and threeratios that are equivalent to 100%. A promising new chef opens a restaurant in your city and considers local food supply chains the best way to feature regional flavors on her menu. Compose a one-paragraph entry for a single menu item an entree, appetizer or dessertand describe three ingredients used in its creation. Include a backstory for each ingredient and explain how it is a part of the local food supply chain. Include two benefits of utilizing a local food supply chain rather than a global. Hey, just wanted to say happy birthday and congrats on getting into columbia. i knew you could do it and am so proud of you. hope you've been doing ok. you don't have to respond to this but i just wanted to tell you that im happy for you. explain how protesting pulls pressure on employers of farm workers to improve their working conditions in a short and simple setence.please help asap thank u so much! How do you find the slope of a logarithmic function? based on your current knowledge and work experience, which strategic training and development initiatives do you think that all companies should support regardless of economic conditions Find the area of the largest rectangle that can be inscribed in the ellipse x2 / a2 + y2 / b2 = 1. What did the Mexican Cession do?A.It gave the southeast region to the U.S.B.It gave the northeast region to the U.S.C.It gave the southwest region to the U.S. Terrence made a scale drawing of a boarding school. The scale he used was7 centimeters: 3 meters. If the actual length of a building at the school is 300 meters, howon is the building in the drawing? A jet is flying with an air speed of 480 miles per hour at a bearing of N82 E. Because of the wind, NE . the ground speed of the plane is 518 miles per hour at a bearing of 79E.a- What are the speed and direction of the wind? b- If the pilot increased the air speed of the plane to 500 miles per hour, what would be the resulting ground speed and direction of the plane? 2x+2y=-6 what is it solved into a y=Mx+b